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与减肥补充剂相关的心肌病:一例病例报告及文献综述

Cardiomyopathy Related to a Weight Loss Supplement: A Case Report and Review of Literature.

作者信息

Murtaza Ghulam, Adhikari Sujeen, Siddiqui Irfan, Lu Hannah, Kuruvilla Aneesh

机构信息

Advocate Christ Medical Center, Oak Lawn, IL, USA.

Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.

出版信息

J Investig Med High Impact Case Rep. 2017 Jun 2;5(2):2324709617711462. doi: 10.1177/2324709617711462. eCollection 2017 Apr-Jun.

DOI:10.1177/2324709617711462
PMID:28616440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5459224/
Abstract

There are various etiologies of dilated cardiomyopathy. However, in young patients without a strong family history of cardiovascular disease, alcohol or drug abuse, viral infections, and absence of endocrine and metabolic abnormalities, ischemia is an unlikely cause. We present an interesting case of a young female without traditional risk factors who developed dilated cardiomyopathy following administration of a weight loss supplement xenadrine and had resolution of symptoms after discontinuation of the supplement.

摘要

扩张型心肌病有多种病因。然而,对于没有心血管疾病家族史、酗酒或药物滥用、病毒感染且无内分泌和代谢异常的年轻患者,缺血不太可能是病因。我们报告了一例有趣的病例,一名年轻女性没有传统风险因素,在服用减肥补充剂西奈君后发生了扩张型心肌病,停用该补充剂后症状缓解。

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本文引用的文献

1
Transient Cardiomyopathy and Quadriplegia Induced by Ephedrine Decongestant.麻黄碱减充血剂诱发的短暂性心肌病和四肢瘫痪
Tex Heart Inst J. 2015 Dec 1;42(6):575-8. doi: 10.14503/THIJ-14-4487. eCollection 2015 Dec.
2
Long-term prognostic impact of therapeutic strategies in patients with idiopathic dilated cardiomyopathy: changing mortality over the last 30 years.特发性扩张型心肌病患者治疗策略的长期预后影响:过去 30 年死亡率的变化。
Eur J Heart Fail. 2014 Mar;16(3):317-24. doi: 10.1002/ejhf.16. Epub 2013 Dec 14.
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Short-term metabolic and hemodynamic effects of ephedra and guarana combinations.麻黄与瓜拉那组合的短期代谢及血流动力学效应
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4
Caffeine-herbal ephedra combination increases resting energy expenditure, heart rate and blood pressure.咖啡因与麻黄草的组合会增加静息能量消耗、心率和血压。
Clin Exp Pharmacol Physiol. 2005 Jan-Feb;32(1-2):47-53. doi: 10.1111/j.1440-1681.2005.04152.x.
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Is there an association between ephedra and heart failure? a case series.
J Card Fail. 2005 Feb;11(1):9-11. doi: 10.1016/j.cardfail.2004.04.003.
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The relative safety of ephedra compared with other herbal products.麻黄与其他草药产品相比的相对安全性。
Ann Intern Med. 2003 Mar 18;138(6):468-71. doi: 10.7326/0003-4819-138-6-200303180-00010.
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Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids.与含有麻黄生物碱的膳食补充剂相关的不良心血管和中枢神经系统事件。
N Engl J Med. 2000 Dec 21;343(25):1833-8. doi: 10.1056/NEJM200012213432502.
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Ephedrine abuse causing acute myocardial infarction.
Med J Aust. 1997 Aug 18;167(4):199-200. doi: 10.5694/j.1326-5377.1997.tb138845.x.