• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

撤回:FADD 和 Caspase-8 的过表达抑制人胶质母细胞瘤细胞的增殖并促进其凋亡。

RETRACTED: Overexpression of FADD and Caspase-8 inhibits proliferation and promotes apoptosis of human glioblastoma cells.

机构信息

Department of Neurosurgery, Affiliated Hospital of Hebei University of Engineering, Handan 056029, PR China.

Department of Rehabilitation, Xingtai Hospital of Traditional Chinese Medicine, Xingtai 054000, PR China.

出版信息

Biomed Pharmacother. 2017 Sep;93:1-7. doi: 10.1016/j.biopha.2017.05.105. Epub 2017 Jun 12.

DOI:10.1016/j.biopha.2017.05.105
PMID:28618251
Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. An Expression of Concern for this article was previously published while an investigation was conducted (see related editorial: https://doi.org/10.1016/j.biopha.2022.113812). This retraction notice supersedes the Expression of Concern published earlier. Concern was raised about the reliability of the Western blot data in Figure 1B, which appear to represent a distinct phenotype found in many other publications, as detailed here: https://pubpeer.com/publications/52B13D77036B8927AFCF19CEFA0991; and here: https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249. Concerns were also expressed over the unusual flow cytometry plots in Figure 3A, and the provenance of these data. The journal requested the corresponding author comment on these concerns and provide the associated raw data. The authors did not respond to this request and therefore the Editor-in-Chief decided to retract the article.

摘要

本文已被撤回

请参阅 Elsevier 撤稿政策(http://www.elsevier.com/locate/withdrawalpolicy)。应主编要求撤回本文。在进行调查时,曾发表过一篇对此文的关注声明(参见相关社论:https://doi.org/10.1016/j.biopha.2022.113812)。本撤稿通知取代了之前发表的关注声明。人们对图 1B 中的 Western blot 数据的可靠性提出了质疑,这些数据似乎代表了许多其他出版物中发现的明显表型,详见此处:https://pubpeer.com/publications/52B13D77036B8927AFCF19CEFA0991;以及此处:https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249。人们还对图 3A 中异常的流式细胞术图谱以及这些数据的来源表示担忧。期刊要求通讯作者对这些问题发表评论并提供相关原始数据。作者未对此请求作出回应,因此主编决定撤回该文章。

相似文献

1
RETRACTED: Overexpression of FADD and Caspase-8 inhibits proliferation and promotes apoptosis of human glioblastoma cells.撤回:FADD 和 Caspase-8 的过表达抑制人胶质母细胞瘤细胞的增殖并促进其凋亡。
Biomed Pharmacother. 2017 Sep;93:1-7. doi: 10.1016/j.biopha.2017.05.105. Epub 2017 Jun 12.
2
RETRACTED: MicroRNA-497 promotes proliferation and inhibits apoptosis of cardiomyocytes through the downregulation of Mfn2 in a mouse model of myocardial ischemia-reperfusion injury.撤回:微小 RNA-497 通过下调心肌缺血再灌注损伤小鼠模型中的 Mfn2 促进心肌细胞增殖和抑制凋亡。
Biomed Pharmacother. 2018 Sep;105:103-114. doi: 10.1016/j.biopha.2018.04.181. Epub 2018 May 28.
3
RETRACTED: Matrine inhibits hypoxia/reoxygenation-induced apoptosis of cardiac microvascular endothelial cells in rats via the JAK2/STAT3 signaling pathway.撤回:苦参碱通过 JAK2/STAT3 信号通路抑制大鼠心肌微血管内皮细胞缺氧/复氧诱导的细胞凋亡。
Biomed Pharmacother. 2018 Oct;106:117-124. doi: 10.1016/j.biopha.2018.06.003. Epub 2018 Jun 26.
4
RETRACTED: Ophiopogonin B induces the autophagy and apoptosis of colon cancer cells by activating JNK/c-Jun signaling pathway.撤回:麦冬总甾体 B 通过激活 JNK/c-Jun 信号通路诱导结肠癌细胞自噬和凋亡。
Biomed Pharmacother. 2018 Dec;108:1208-1215. doi: 10.1016/j.biopha.2018.06.172. Epub 2018 Oct 2.
5
RETRACTED: MicroRNA138 regulates keratin 17 protein expression to affect HaCaT cell proliferation and apoptosis by targeting hTERT in psoriasis vulgaris.撤回:微小RNA138通过靶向寻常型银屑病中的hTERT调节角蛋白17蛋白表达,影响HaCaT细胞增殖和凋亡。
Biomed Pharmacother. 2017 Jan;85:169-176. doi: 10.1016/j.biopha.2016.11.085. Epub 2016 Dec 6.
6
RETRACTED: The effects of tanshinone IIA on hypoxia/reoxygenation-induced myocardial microvascular endothelial cell apoptosis in rats via the JAK2/STAT3 signaling pathway.撤回:丹参酮 IIA 通过 JAK2/STAT3 信号通路对缺氧/复氧诱导的大鼠心肌微血管内皮细胞凋亡的影响。
Biomed Pharmacother. 2016 Oct;83:1116-1126. doi: 10.1016/j.biopha.2016.07.054. Epub 2016 Aug 20.
7
RETRACTED: miR-539 enhances chemosensitivity to cisplatin in non-small cell lung cancer by targeting DCLK1.撤回:miR-539 通过靶向 DCLK1 增强非小细胞肺癌对顺铂的化疗敏感性。
Biomed Pharmacother. 2018 Oct;106:1072-1081. doi: 10.1016/j.biopha.2018.07.024. Epub 2018 Jul 17.
8
RETRACTED: Protective effects of total flavonoids in Caragana against hypoxia/reoxygenation-induced injury in human brain microvascular endothelial cells.撤回:锦鸡儿总黄酮对缺氧/复氧诱导的人脑血管内皮细胞损伤的保护作用。
Biomed Pharmacother. 2017 May;89:316-322. doi: 10.1016/j.biopha.2017.01.106. Epub 2017 Feb 24.
9
RETRACTED: The effects of the long non-coding RNA MALAT-1 regulated autophagy-related signaling pathway on chemotherapy resistance in diffuse large B-cell lymphoma.撤回:长链非编码RNA MALAT-1调控的自噬相关信号通路对弥漫性大B细胞淋巴瘤化疗耐药性的影响
Biomed Pharmacother. 2017 May;89:939-948. doi: 10.1016/j.biopha.2017.02.011. Epub 2017 Mar 8.
10
RETRACTED: Effects of Artesunate on chondrocyte proliferation, apoptosis and autophagy through the PI3K/AKT/mTOR signaling pathway in rat models with rheumatoid arthritis.撤回:青蒿琥酯通过 PI3K/AKT/mTOR 信号通路对类风湿性关节炎大鼠模型软骨细胞增殖、凋亡和自噬的影响。
Biomed Pharmacother. 2018 Jun;102:1209-1220. doi: 10.1016/j.biopha.2018.03.142. Epub 2018 Apr 7.

引用本文的文献

1
Cell death in glioblastoma and the central nervous system.胶质母细胞瘤和中枢神经系统中的细胞死亡
Cell Oncol (Dordr). 2025 Apr;48(2):313-349. doi: 10.1007/s13402-024-01007-8. Epub 2024 Nov 6.
2
Changes in the expression of cancer- and metastasis-related genes and proteins after metformin treatment under different metabolic conditions in endometrial cancer cells.在不同代谢条件下,二甲双胍处理子宫内膜癌细胞后癌症和转移相关基因及蛋白表达的变化
Heliyon. 2023 May 25;9(6):e16678. doi: 10.1016/j.heliyon.2023.e16678. eCollection 2023 Jun.
3
Burn-Induced Apoptosis in the Livers of Aged Mice Is Associated With Caspase Cleavage of Bcl-xL.
衰老小鼠肝脏中的烧伤诱导凋亡与 Bcl-xL 的半胱天冬酶切割有关。
J Surg Res. 2023 Oct;290:147-155. doi: 10.1016/j.jss.2023.04.020. Epub 2023 May 31.
4
The dual role of the CD95 and CD95L signaling pathway in glioblastoma.CD95 及其配体信号通路在胶质母细胞瘤中的双重作用。
Front Immunol. 2022 Nov 24;13:1029737. doi: 10.3389/fimmu.2022.1029737. eCollection 2022.
5
FADD as a key molecular player in cancer progression.FADD 作为癌症进展中的关键分子参与者。
Mol Med. 2022 Nov 8;28(1):132. doi: 10.1186/s10020-022-00560-y.
6
Machine learning identification of cuproptosis and necroptosis-associated molecular subtypes to aid in prognosis assessment and immunotherapy response prediction in low-grade glioma.基于机器学习的铜死亡和坏死性凋亡相关分子亚型鉴定,以辅助低级别胶质瘤的预后评估和免疫治疗反应预测。
Front Genet. 2022 Sep 12;13:951239. doi: 10.3389/fgene.2022.951239. eCollection 2022.
7
A causal variant rs3769823 in 2q33.1 involved in apoptosis pathway leading to a decreased risk of non-small cell lung cancer.一个位于 2q33.1 上的与凋亡通路相关的因果变异 rs3769823,可降低非小细胞肺癌的发病风险。
Cancer Biol Med. 2022 Sep 2;19(9):1385-96. doi: 10.20892/j.issn.2095-3941.2022.0068.
8
HS3ST1 Promotes Non-Small-Cell Lung Cancer Progression by Targeting the SPOP/FADD/NF-B Pathway.HS3ST1 通过靶向 SPOP/FADD/NF-κB 通路促进非小细胞肺癌进展。
Biomed Res Int. 2022 Jul 19;2022:5509346. doi: 10.1155/2022/5509346. eCollection 2022.
9
Pyroptosis-Related Gene to Construct Prognostic Signature and Explore Immune Microenvironment and Immunotherapy Biomarkers in Bladder Cancer.构建用于预测膀胱癌预后的焦亡相关基因特征并探索免疫微环境及免疫治疗生物标志物
Front Genet. 2022 Jul 1;13:801665. doi: 10.3389/fgene.2022.801665. eCollection 2022.
10
Alterations in Molecular Profiles Affecting Glioblastoma Resistance to Radiochemotherapy: Where Does the Good Go?影响胶质母细胞瘤对放化疗耐药性的分子特征改变:优势何在?
Cancers (Basel). 2022 May 13;14(10):2416. doi: 10.3390/cancers14102416.