Sut Stefania, Pavela Roman, Kolarčik Vladislav, Cappellacci Loredana, Petrelli Riccardo, Maggi Filippo, Dall'Acqua Stefano, Benelli Giovanni
Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Marzolo, 35121 Padova, Italy.
Crop Research Institute, Drnovska 507, 161 06, Prague 6, Czech Republic.
Molecules. 2017 Jun 16;22(6):1002. doi: 10.3390/molecules22061002.
There is an increasing need for the discovery of reliable and eco-friendly pesticides and natural plant-derived products may play a crucial role as source of new active compounds. In this research, a lipophilic extract of roots extract containing 12% of shikonin derivatives demonstrated significant toxicity and inhibition of oviposition against mites. Extensive chromatographic separation allowed the isolation of 11 naphthoquinone derivatives that were identified by spectral techniques and were tested against . All the isolated compounds presented effects against the considered mite and isobutylshikonin () and isovalerylshikonin () were the most active, being valuable model compounds for the study of new anti-mite agents.
对可靠且环保型杀虫剂的需求日益增长，天然植物源产品可能作为新活性化合物的来源发挥关键作用。在本研究中，一种含有12%紫草素衍生物的根提取物的亲脂性提取物对螨虫表现出显著毒性和产卵抑制作用。通过广泛的色谱分离，分离出了11种萘醌衍生物，这些衍生物通过光谱技术进行了鉴定，并针对[此处原文缺失测试对象]进行了测试。所有分离出的化合物对所研究的螨虫均有作用，异丁基紫草素（）和异戊酰紫草素（）活性最强，是研究新型抗螨剂的有价值的模型化合物。
