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天然来源阿魏酸的潜在应用。

Potential applications of ferulic acid from natural sources.

作者信息

Kumar Naresh, Pruthi Vikas

机构信息

Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, India.

出版信息

Biotechnol Rep (Amst). 2014 Sep 16;4:86-93. doi: 10.1016/j.btre.2014.09.002. eCollection 2014 Dec.

Abstract

Ferulic acid (FA), a ubiquitous natural phenolic phytochemical present in seeds, leaves, bothin its free form and covalently conjugated to the plant cell wall polysaccharides, glycoproteins,polyamines, lignin and hydroxy fatty acids. FA plays a vital role in providing the rigidity to the cell wall and formation of other important organic compounds like coniferyl alcohol, vanillin, sinapic, diferulic acid and curcumin. FA exhibits wide variety of biological activities such as antioxidant, antiinflammatory, antimicrobial, antiallergic, hepatoprotective, anticarcinogenic, antithrombotic, increase sperm viability, antiviral and vasodilatory actions, metal chelation, modulation of enzyme activity, activation of transcriptional factors, gene expression and signal transduction.

摘要

阿魏酸(FA)是一种广泛存在的天然酚类植物化学物质,存在于种子、叶子中,以游离形式以及与植物细胞壁多糖、糖蛋白、多胺、木质素和羟基脂肪酸共价结合的形式存在。阿魏酸在赋予细胞壁刚性以及形成其他重要有机化合物(如松柏醇、香草醛、芥子酸、二阿魏酸和姜黄素)方面起着至关重要的作用。阿魏酸具有多种生物活性,如抗氧化、抗炎、抗菌、抗过敏、保肝、抗癌、抗血栓形成、提高精子活力、抗病毒和血管舒张作用、金属螯合、调节酶活性、激活转录因子、基因表达和信号转导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1942/5466124/e97074f58b6a/gr1.jpg

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