The Danish National Academy of Music, Odense, Denmark.
Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Psychooncology. 2018 Feb;27(2):386-400. doi: 10.1002/pon.4470. Epub 2017 Aug 16.
Music may be a valuable and low-cost coping strategy for cancer patients. We conducted a systematic review and meta-analysis to identify the psychological and physical effects of music interventions in cancer treatment.
We included randomized, controlled trials with adult patients in active cancer treatment exposed to different music interventions versus control conditions. Qualitative studies and systematic reviews were excluded. We identified a total of 2624 records through 2 systematic searches (June 2015 and September 2016) in PubMed, Scopus, EMBASE, Cinahl, Web of Science, Cochrane, and PsycINFO and used Risk of Bias Assessment, GRADE and Checklist for Reporting Music-Based Interventions to evaluate the music applied and quality of the studies. We conducted meta-analyses using Review Manager (version 5.3). PROSPERO reg. no. CRD42015026024.
We included 25 RCT's (N = 1784) of which 20 were eligible for the meta-analysis (N = 1565). Music reduced anxiety (SMD -0·80 [95% CI, -1.35 to -0.25]), pain (SMD -0.88 [95% CI -1.45 to -0.32]), and improved mood (SMD -0.55 [95% CI, -0.98 to -0.13]). However, studies were hampered by heterogeneity with I varying between 54% and 96%. Quality of the studies ranged from very low to low. The most effective mode of music intervention appeared to be passive listening to self-selected, recorded music in a single session design.
Music may be a tool in reducing anxiety, pain, and improving mood among patients with cancer in active treatment. However, methodological limitations in the studies conducted so far prevent firm conclusions.
音乐可能是癌症患者一种有价值且低成本的应对策略。我们进行了系统评价和荟萃分析，以确定音乐干预在癌症治疗中的心理和生理影响。
我们纳入了接受不同音乐干预与对照条件的成年癌症患者的随机对照试验。排除了定性研究和系统评价。我们通过 2 次系统搜索（2015 年 6 月和 2016 年 9 月）在 PubMed、Scopus、EMBASE、Cinahl、Web of Science、Cochrane 和 PsycINFO 中总共确定了 2624 条记录，并使用风险偏倚评估、GRADE 和音乐干预报告检查表来评估所应用的音乐和研究的质量。我们使用 Review Manager（版本 5.3）进行荟萃分析。PROSPERO 注册号 CRD42015026024。
我们纳入了 25 项 RCT（N=1784），其中 20 项符合荟萃分析条件（N=1565）。音乐降低了焦虑（SMD -0.80 [95% CI，-1.35 至 -0.25]）、疼痛（SMD -0.88 [95% CI，-1.45 至 -0.32]）和改善了情绪（SMD -0.55 [95% CI，-0.98 至 -0.13]）。然而，由于研究存在异质性（I 为 54% 至 96%），研究受到阻碍。研究质量从极低到低不等。音乐干预最有效的模式似乎是单次设计中被动聆听自选的、录制的音乐。
音乐可能是减轻癌症患者积极治疗中焦虑、疼痛和改善情绪的一种工具。然而，到目前为止进行的研究中的方法学局限性阻止了我们得出明确的结论。
