Rehn D, Haack D, Vecsei P, Hennings G
Arzneimittelforschung. 1985;35(6):970-2.
Plasma hydrocortisone (cortisol) levels in 7 healthy volunteers were measured following administration of 0.25 mg betamethasone or 0.25 mg betamethasone and 1 mg dimetindene maleate. The H1-receptor antagonist dimetindene maleate did not influence the hydrocortisone suppressing activity of betamethasone, which was proved by comparison with the published plasma hydrocortisone levels of 162 young healthy untreated volunteers.
在7名健康志愿者服用0.25毫克倍他米松或0.25毫克倍他米松与1毫克马来酸氯苯那敏后，测量其血浆氢化可的松（皮质醇）水平。通过与162名未接受治疗的年轻健康志愿者已发表的血浆氢化可的松水平进行比较，证明H1受体拮抗剂马来酸氯苯那敏不会影响倍他米松的氢化可的松抑制活性。
