Kristenson H, Hood B, Peterson B, Trell E
Alcohol. 1985 May-Jun;2(3):545-9. doi: 10.1016/0741-8329(85)90132-6.
More than 30,000 individuals have been investigated in the continuous screening and intervention study in Malmö. Large subsamples of individuals with different levels of GGT (gamma-glutamyltransferase) have been characterized. GGT has proven to be a useful and simple tool in tracing, identifying, treating and controlling heavy drinkers. Furthermore, GGT seems to be a new and strong indicator of alcohol-related disabilities and short term mortality in the male population. Individuals with GGT in the tenth deecentile of the GGT distribution have been randomly selected for treatment or control. Results and follow-up for 60 months in the intervention study with randomized controls in middle-aged heavy drinkers indicate a significant reduction in alcohol consumption, sick absence, hospitalization and mortality. Thus, the intervention program seems to be effective in preventing complications of alcoholism on an individual basis.
在马尔默进行的持续筛查和干预研究中，已有超过30000人接受了调查。对不同γ-谷氨酰转移酶（GGT）水平的个体进行了大量子样本分析。GGT已被证明是追踪、识别、治疗和控制酗酒者的一种有用且简单的工具。此外，GGT似乎是男性人群中与酒精相关残疾和短期死亡率的一个新的重要指标。已从GGT分布的第十分位数中随机选择GGT水平的个体进行治疗或对照。对中年酗酒者进行随机对照干预研究的60个月结果和随访表明，酒精消费量、病假缺勤率、住院率和死亡率均显著降低。因此，该干预计划似乎在个体层面上有效预防了酒精中毒的并发症。
