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硅烷配体修饰氧化石墨烯的合成及修饰石墨烯-银纳米复合材料的抗菌活性。

Synthesis of silane ligand-modified graphene oxide and antibacterial activity of modified graphene-silver nanocomposite.

机构信息

Department of Chemistry, Payame Noor University, PO Box: 19395-3697, Tehran, Iran.

Department of Chemistry, Payame Noor University, PO Box: 19395-3697, Tehran, Iran.

出版信息

Mater Sci Eng C Mater Biol Appl. 2017 Oct 1;79:55-65. doi: 10.1016/j.msec.2017.05.020. Epub 2017 May 5.

Abstract

In this research, a new type of chemically modified graphene oxide (GO) was synthesized based a silane ligand and then used as substrate and stabilizing for the synthesis of monodispersed and small Ag nanoparticles (NPs). First, ligand molecules were successfully grafted onto the surface of GO (LGO) and then, active groups of LGO could effectively interact with Ag ions. The reduction of Ag ions and LGO sheets was carried out by hydrazine under reflux. The resulted nanocomposite was fully characterized by different techniques. Furthermore, the antibacterial behavior of nanocomposite was studied against E. coli and S. aureus. The results showed that nanocomposite exhibits good antibacterial activity against E. coli and S. aureus and also S. aureus showed greater resistance than the E. coli strains against the LG/Ag nanocomposite.

摘要

在这项研究中,基于硅烷配体合成了一种新型化学改性氧化石墨烯(GO),然后将其用作合成单分散和小尺寸银纳米粒子(NPs)的基底和稳定剂。首先,成功地将配体分子接枝到 GO 表面(LGO)上,然后,LGO 的活性基团可以与 Ag 离子有效相互作用。在回流条件下,通过水合肼还原 Ag 离子和 LGO 片。通过不同的技术对所得纳米复合材料进行了充分的表征。此外,还研究了纳米复合材料对大肠杆菌和金黄色葡萄球菌的抗菌行为。结果表明,纳米复合材料对大肠杆菌和金黄色葡萄球菌表现出良好的抗菌活性,并且金黄色葡萄球菌对 LG/Ag 纳米复合材料的抗性大于大肠杆菌菌株。

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