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棉/银/石墨烯量子点(cotton/Ag/GQDs)纳米复合材料的合成与表征及其作为新型抗菌纳米垫的应用。

Synthesis and characterization of cotton-silver-graphene quantum dots (cotton/Ag/GQDs) nanocomposite as a new antibacterial nanopad.

机构信息

Institute of Nano Science and Nano Technology, University of Kashan, Kashan, P. O. Box. 87317-51167, Iran; Trita Nanomedicine Research Center (TNRC), Trita Third Millennium Pharmaceuticals, 45331-55681, Zanjan, Iran.

Department of Chemistry, College of Science, University of Raparin, Rania, Kurdistan Region, Iraq; Department of Chemistry, College of Science, International University of Erbil, Iraq.

出版信息

Chemosphere. 2021 Mar;267:129293. doi: 10.1016/j.chemosphere.2020.129293. Epub 2020 Dec 11.

Abstract

Appearance of antibiotic resistance in bacteria is a convoluted topic, particularly in treating pestiferous immunodeficiency correlated diseases. The main objective of the current research is to fabricate antibacterial pads by utilizing of graphene quantum dots (GQDs) as a linker, stabilizing, and reduction agent of in situ synthesized Ag nanoparticles (Ag NPs) on cotton pad. Five different antibacterial pads including cotton/Ag pad, cotton/GQDs/Ag pad, cotton/Ag/GQDs pad, cotton/GQDs/Ag/GQDs pad, and cotton/Ag/GQDs/Ag were fabricated and their antibacterial activities were compared to those of as-synthesized Ag/GQDs nanocomposites. The results indicate that cotton/GQDs/Ag pad shows a very promising minimum inhibitory concentration(MIC) of 0.09 and 0.01 against S. aureus and E. coli, respectively. Using GQDs as a linker (cotton/GQDs/Ag) and as a stabilizing agent (cotton/Ag/GQDs) significantly improves the antibacterial activity of Ag NPs.

摘要

细菌对抗生素耐药性的出现是一个复杂的问题,特别是在治疗可恶的免疫缺陷相关疾病时。本研究的主要目的是利用石墨烯量子点 (GQDs) 作为连接剂、稳定剂和原位合成的 Ag 纳米粒子 (Ag NPs) 在棉垫上的还原剂来制备抗菌垫。我们制备了五种不同的抗菌垫,包括棉/Ag 垫、棉/GQDs/Ag 垫、棉/Ag/GQDs 垫、棉/GQDs/Ag/GQDs 垫和棉/Ag/GQDs/Ag,并将它们的抗菌活性与合成的 Ag/GQDs 纳米复合材料进行了比较。结果表明,棉/GQDs/Ag 垫对金黄色葡萄球菌和大肠杆菌的最小抑菌浓度 (MIC) 分别为 0.09 和 0.01。使用 GQDs 作为连接剂 (棉/GQDs/Ag) 和稳定剂 (棉/Ag/GQDs) 可显著提高 Ag NPs 的抗菌活性。

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