PET-CT Center, the First People's Hospital of Yunnan Province, Kunming 650032, Yunnan Province, China.
Nanfang PET Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
World J Gastroenterol. 2019 Aug 28;25(32):4682-4695. doi: 10.3748/wjg.v25.i32.4682.
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer mortality worldwide. Various imaging modalities provide important information about HCC for its clinical management. Since positron-emission tomography (PET) or PET-computed tomography was introduced to the oncologic setting, it has played crucial roles in detecting, distinguishing, accurately staging, and evaluating local, residual, and recurrent HCC. PET imaging visualizes tissue metabolic information that is closely associated with treatment. Dynamic PET imaging and dual-tracer have emerged as complementary techniques that aid in various aspects of HCC diagnosis. The advent of new radiotracers and the development of immuno-PET and PET-magnetic resonance imaging have improved the ability to detect lesions and have made great progress in treatment surveillance. The current PET diagnostic capabilities for HCC and the supplementary techniques are reviewed herein.
肝细胞癌（HCC）是全球癌症死亡的主要原因之一。各种影像学方法为 HCC 的临床管理提供了重要的信息。自从正电子发射断层扫描（PET）或 PET-计算机断层扫描被引入肿瘤学领域以来，它在检测、鉴别、准确分期和评估局部、残留和复发性 HCC 方面发挥了关键作用。PET 成像可以可视化与治疗密切相关的组织代谢信息。动态 PET 成像和双示踪剂已成为互补技术，有助于 HCC 诊断的各个方面。新型放射性示踪剂的出现以及免疫 PET 和 PET-磁共振成像的发展提高了检测病灶的能力，并在治疗监测方面取得了重大进展。本文回顾了 HCC 的当前 PET 诊断能力和补充技术。
