Fei Jun, Gu Jianhua
Department of Orthopaedics, Hospital of Integrated Traditional and Western Medicine of Zhejiang, Hangzhou, Zhejiang, China (mainland).
Department of Trauma and Orthopaedics, Shanghai Ninth People's Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China (mainland).
Med Sci Monit. 2017 Jun 20;23:3010-3018. doi: 10.12659/msm.901868.
BACKGROUND The main purpose of this study was to compare the effects of various lavage techniques - traditional saline lavage (SL), pulse lavage (PL), closed drainage (CD), and iodine lavage (IL) - on preventing incision-related infection after posterior lumbar interbody fusion. MATERIAL AND METHODS Patients with prolapsed lumbar (intervertebral) discs (PLID) undergoing posterior lumbar interbody fusion surgery (PLIF) over the course of 2 years were included and were randomly allocated into 4 groups: the SL group, the PL group, the CD group, and the IL group. Relevant data were recorded, including preoperative conditions, intraoperative lavage time, lavage fluid volume, incision outlook, pain perception, results of routine blood tests, and postoperative infection rate. RESULTS The PL, CD, and IL groups showed less intraoperative lavage time, lavage volume fluid, effusion, infection rate, and muscle and lower pain perception compared with the SL group (all P<0.05). Significant differences in white blood cell (WBC) count, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) were observed between preoperative and postoperative data in each group (P<0.01). No significant differences in clinical characteristics, postoperative temperature, suture removal time, incision characteristics, WBC, ESR, and CRP were observed among the PL, CD, IL, and SL groups (P>0.05). CONCLUSIONS PL, CD, and IL all showed much better postoperative infection prevention in comparison to SL.
背景 本研究的主要目的是比较各种灌洗技术——传统生理盐水灌洗(SL)、脉冲灌洗(PL)、闭式引流(CD)和碘伏灌洗(IL)——对预防腰椎后路椎间融合术后切口相关感染的效果。
材料与方法 纳入2年内接受腰椎后路椎间融合手术(PLIF)的腰椎间盘突出症(PLID)患者,并将其随机分为4组:SL组、PL组、CD组和IL组。记录相关数据,包括术前情况、术中灌洗时间、灌洗液体量、切口外观、疼痛感知、血常规检查结果及术后感染率。
结果 与SL组相比,PL组、CD组和IL组术中灌洗时间、灌洗液体量、积液、感染率及肌肉疼痛感知均较低(均P<0.05)。每组术前和术后数据的白细胞(WBC)计数、红细胞沉降率(ESR)和C反应蛋白(CRP)有显著差异(P<0.01)。PL组、CD组、IL组和SL组在临床特征、术后体温、拆线时间、切口特征、WBC、ESR和CRP方面无显著差异(P>0.05)。
结论 与SL相比,PL、CD和IL在预防术后感染方面均表现出更好的效果。