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铅中毒很容易被误诊为急性卟啉病和非特异性腹痛。

Lead Poisoning Can Be Easily Misdiagnosed as Acute Porphyria and Nonspecific Abdominal Pain.

作者信息

Tsai Ming-Ta, Huang Shi-Yu, Cheng Shih-Yu

机构信息

Department of Emergency Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

出版信息

Case Rep Emerg Med. 2017;2017:9050713. doi: 10.1155/2017/9050713. Epub 2017 May 29.

DOI:10.1155/2017/9050713
PMID:28630774
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5467293/
Abstract

Lead poisoning (LP) is less commonly encountered in emergency departments (ED). However, lead exposure still occurs, and new sources of poisoning have emerged. LP often goes unrecognized due to a low index of suspicion and nonspecific symptoms. We present a case of a 48-year-old man who had recurring abdominal pain with anemia that was misdiagnosed. His condition was initially diagnosed as nonspecific abdominal pain and acute porphyria. Acute porphyria-like symptoms with a positive urine porphyrin test result led to the misdiagnosis; testing for heme precursors in urine is the key to the differential diagnosis between LP and acute porphyria. The final definitive diagnosis of lead toxicity was confirmed based on high blood lead levels after detailed medical history taking. The lead poisoning was caused by traditional Chinese herbal pills. The abdominal pain disappeared after a course of chelating treatment. The triad for the diagnosis of lead poisoning should be a history of medicine intake, anemia with basophilic stippling, and recurrent abdominal pain.

摘要

铅中毒(LP)在急诊科较少见。然而,铅暴露仍有发生,且出现了新的中毒源。由于怀疑指数低和症状不具特异性,铅中毒常未被识别。我们报告一例48岁男性病例,该患者反复腹痛伴贫血,曾被误诊。其病情最初被诊断为非特异性腹痛和急性卟啉病。尿卟啉试验结果呈阳性的急性卟啉病样症状导致了误诊;检测尿中的血红素前体是鉴别铅中毒和急性卟啉病的关键。在详细询问病史后,根据高血铅水平确诊为铅中毒。铅中毒是由中药丸引起的。经过一个疗程的螯合治疗后,腹痛消失。铅中毒诊断的三联征应为用药史、伴有嗜碱性点彩的贫血和反复腹痛。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c3d/5467293/35e946cf182a/CRIEM2017-9050713.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c3d/5467293/35e946cf182a/CRIEM2017-9050713.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c3d/5467293/35e946cf182a/CRIEM2017-9050713.001.jpg

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Indian J Clin Biochem. 2013 Jan;28(1):1-2. doi: 10.1007/s12291-012-0290-z.
2
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Korean J Intern Med. 2013 Jul;28(4):504-6. doi: 10.3904/kjim.2013.28.4.504. Epub 2013 Jul 1.
3
Epigenetics of early-life lead exposure and effects on brain development.早期铅暴露的表观遗传学及其对大脑发育的影响。
传统医学和替代医学导致的铅中毒和砷中毒:男性比女性更敏感。
Naunyn Schmiedebergs Arch Pharmacol. 2025 Jan;398(1):799-818. doi: 10.1007/s00210-024-03317-y. Epub 2024 Jul 27.
4
Heavy metal poisoning caused by Chinese folk remedies in psoriasis patients: a retrospective analysis.重金属中毒由中国民间疗法引起的银屑病患者:回顾性分析。
Sci Rep. 2024 May 23;14(1):11777. doi: 10.1038/s41598-024-62653-4.
5
Abnormal Porphyrin Metabolism in Autism Spectrum Disorder and Therapeutic Implications.自闭症谱系障碍中的异常卟啉代谢及其治疗意义。
Mol Neurobiol. 2024 Jul;61(7):3851-3866. doi: 10.1007/s12035-023-03722-z. Epub 2023 Nov 30.
6
Cryptogenic Abdominal Pain: Recognizing False Leads.隐匿性腹痛:识别假线索。
Am J Case Rep. 2023 Jun 9;24:e939504. doi: 10.12659/AJCR.939504.
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9
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BMC Med Inform Decis Mak. 2023 Feb 2;23(1):26. doi: 10.1186/s12911-023-02123-5.
10
Investigation on the elemental profiles of lip cosmetic products: Concentrations, distribution and assessment of potential carcinogenic and non-carcinogenic human health risk for consumer safety.唇部化妆品的元素特征研究:浓度、分布以及对消费者安全的潜在致癌和非致癌人体健康风险评估。
Saudi Pharm J. 2022 Jun;30(6):779-792. doi: 10.1016/j.jsps.2022.03.014. Epub 2022 Mar 30.
Epigenomics. 2012 Dec;4(6):665-74. doi: 10.2217/epi.12.58.
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BMC Genomics. 2012 Jul 27;13:344. doi: 10.1186/1471-2164-13-344.
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Am J Ind Med. 2005 Feb;47(2):172-5. doi: 10.1002/ajim.20123.