Yaguchi Yoshihisa, Kumata Yoshimasa, Horikawa Masahiro, Kiyokawa Takashi, Inaba Tsuyoshi, Fukushima Ryoji
Department of Surgery, Teikyo University School of Medicine, 2-11-1, Kaga, Itabashi-ku, Tokyo, 173-8605, Japan.
Surg Case Rep. 2017 Dec;3(1):77. doi: 10.1186/s40792-017-0354-7. Epub 2017 Jun 19.
Esophageal perforation after aortic replacement/stenting for aortic dissection or aneurysm is a rare but severe complication. However, its cause, standard treatment, and prognosis are unclear. We analyzed the treatment and outcome retrospectively from seven cases experienced at our hospital.
The median age of the patients was 70 years (range, 41-86), and six of the seven cases were male. As the first treatment, aortic replacement techniques were performed in five, and thoracic endovascular aortic repair (TEVAR) procedure was performed in two. We evaluated the treatment of the perforation, the cause of death, and the median survival time after reparative surgery (esophagectomy). Initial treatment of the perforation was esophagectomy without reconstruction in six and esophagogastric bypass (later, esophagectomy was performed) in one. Three of seven cases could be discharged from hospital or moved to another hospital, but two of these three cases died of major bleeding on postoperative days 320 and 645. The other four esophagectomy cases died in hospital because of sepsis on postoperative days 14, 30, and 41 and major bleeding on postoperative day 54. The one surviving case was a 65-year-old man who underwent reconstruction, and was still alive without signs of infection at 424 days postoperatively.
The prognosis of esophageal perforation cases after aortic replacement/stenting for thoracic aortic dissection or aneurysm is poor, though there were some cases with relatively long survival. Therefore, the indication for invasive esophagectomy should be decided carefully. Control of infection including regional infection is essential for successful treatment.
主动脉夹层或动脉瘤行主动脉置换/支架置入术后发生食管穿孔是一种罕见但严重的并发症。然而,其病因、标准治疗方法及预后尚不清楚。我们回顾性分析了我院收治的7例患者的治疗情况及预后。
患者的中位年龄为70岁(范围41 - 86岁),7例中有6例为男性。作为首次治疗,5例行主动脉置换术,2例行胸主动脉腔内修复术(TEVAR)。我们评估了穿孔的治疗、死亡原因以及修复手术(食管切除术)后的中位生存时间。穿孔的初始治疗中,6例行食管切除未重建,1例行食管胃旁路术(后来进行了食管切除术)。7例中有3例出院或转至其他医院,但这3例中有2例分别在术后320天和645天死于大出血。另外4例食管切除病例分别在术后第14天、30天和41天因脓毒症以及术后第54天因大出血在医院死亡。唯一存活的病例是一名65岁男性,接受了重建手术,术后424天仍存活,无感染迹象。
胸主动脉夹层或动脉瘤行主动脉置换/支架置入术后发生食管穿孔的病例预后较差,尽管有一些病例存活时间相对较长。因此,对于侵入性食管切除术的适应证应谨慎决定。控制包括局部感染在内的感染对于成功治疗至关重要。