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帕金森病中的吞咽问题:临床问题与管理

Swallowing in Parkinson's disease: clinical issues and management.

作者信息

Miller Nick

机构信息

Newcastle University Institute for Ageing, Speech & Language Sciences, George VI Building, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.

出版信息

Neurodegener Dis Manag. 2017 Jun;7(3):205-217. doi: 10.2217/nmt-2017-0006. Epub 2017 Jun 20.

DOI:10.2217/nmt-2017-0006
PMID:28632108
Abstract

Changes to swallowing affect most people with Parkinson's disease (PD). Changes may not initially exercise a decisive impact, but can later pose significant threats to nutritional, hydration and respiratory health and psychosocial quality of life. This review, from a largely clinical viewpoint, outlines the nature of changes in PD and considers the issue of how many people are affected and in what ways. It outlines main approaches to assessment and management, with an emphasis on aspects relevant to PD. Dysphagia contributes to drooling in PD. The review therefore also touches on the nature and management of this condition that has its own set of health and psychosocial quality-of-life issues.

摘要

吞咽功能的改变影响着大多数帕金森病(PD)患者。这些改变最初可能不会产生决定性影响,但随后可能会对营养、水合作用、呼吸健康以及心理社会生活质量构成重大威胁。本综述主要从临床角度概述了帕金森病吞咽功能改变的性质,并探讨了受影响的人数以及受影响的方式等问题。它概述了评估和管理的主要方法,重点关注与帕金森病相关的方面。吞咽困难会导致帕金森病患者流口水。因此,本综述还涉及了这种状况的性质和管理,它有其自身一系列的健康和心理社会生活质量问题。

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1
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引用本文的文献

1
Exploring the Neuropsychological Correlates of Swallowing Disorders in People with Parkinson's Disease: a Cross-Sectional Study.探索帕金森病患者吞咽障碍的神经心理学关联:一项横断面研究。
Dysphagia. 2025 Feb;40(1):292-304. doi: 10.1007/s00455-024-10728-9. Epub 2024 Jun 29.
2
Prevalence and Factors Associated with Drooling in Parkinson's Disease: Results from a Longitudinal Prospective Cohort and Comparison with a Control Group.帕金森病流涎的患病率及相关因素:一项纵向前瞻性队列研究结果并与对照组比较
Parkinsons Dis. 2023 Apr 6;2023:3104425. doi: 10.1155/2023/3104425. eCollection 2023.
3
A protocol for the evaluation of a wearable device for monitoring of symptoms, and cueing for the management of drooling, in people with Parkinson's disease.
用于监测帕金森病患者症状并提示管理流涎的可穿戴设备的评估方案。
PLoS One. 2023 Feb 24;18(2):e0280727. doi: 10.1371/journal.pone.0280727. eCollection 2023.
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Quipazine Elicits Swallowing in the Arterially Perfused Rat Preparation: A Role for Medullary Raphe Nuclei?氯氮平在动脉灌流大鼠制备中诱发吞咽:是否涉及中缝核?
Int J Mol Sci. 2020 Jul 20;21(14):5120. doi: 10.3390/ijms21145120.