对巴西青霉次生代谢及其生物技术潜力的见解。
Insights into Penicillium brasilianum Secondary Metabolism and Its Biotechnological Potential.
作者信息
Bazioli Jaqueline Moraes, Amaral Luciana Da Silva, Fill Taícia Pacheco, Rodrigues-Filho Edson
机构信息
Instituto de Química, Universidade Estadual de Campinas, CP 6154, 13083-970 Campinas, Brazil.
Departamento de Química, Universidade Federal de São Carlos, CP 676, 13.565-905 São Carlos, SP, Brazil.
出版信息
Molecules. 2017 Jun 20;22(6):858. doi: 10.3390/molecules22060858.
Over the past few years has been isolated from many different environmental sources as soil isolates, plant endophytes and onion pathogen. All investigated strains share a great ability to produce bioactive secondary metabolites. Different authors have investigated this great capability and here we summarize the metabolic potential and the biological activities related to ' metabolites with diverse structures. They include secondary metabolites of an alkaloid nature, i.e., 2,5-diketopiperazines, cyclodepsipeptides, meroterpenoids and polyketides. is also described as a great source of enzymes with biotechnological application potential, which is also highlighted in this review. Additionally, this review will focus on several aspects of and interesting genomic insights.
在过去几年中，已从许多不同的环境来源中分离出来，如土壤分离物、植物内生菌和洋葱病原体。所有研究的菌株都具有产生生物活性次生代谢产物的强大能力。不同的作者对这种强大能力进行了研究，在这里我们总结了与具有不同结构的代谢产物相关的代谢潜力和生物活性。它们包括生物碱性质的次生代谢产物，即2,5-二酮哌嗪、环缩肽、聚酮类化合物。还被描述为具有生物技术应用潜力的酶的重要来源，本综述也强调了这一点。此外，本综述将关注几个方面以及有趣的基因组见解。
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