Department of Bioengineering, Stanford University, Stanford, CA 94305, USA; Sainsbury Laboratory, Cambridge University, Cambridge CB2 1LR, UK.
Department of Bioengineering, Stanford University, Stanford, CA 94305, USA; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Curr Biol. 2017 Jun 19;27(12):R592-R594. doi: 10.1016/j.cub.2017.05.017.
Nutrients are required for the multiple biosynthetic pathways that result in cell growth, and faster growth due to increased nutrient supply results in larger cell volume. A new study demonstrates that fatty-acid availability limits growth rate and cell envelope capacity, revealing that fatty-acid synthesis is the primary determinant of cell size in bacteria and in budding yeast.
营养物质是多种生物合成途径所必需的,这些途径导致细胞生长,而由于营养物质供应增加导致的更快生长导致细胞体积增大。一项新的研究表明,脂肪酸的可用性限制了生长速度和细胞包膜容量,揭示了脂肪酸合成是细菌和出芽酵母中细胞大小的主要决定因素。