Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), National Clinical Research Center on Mental Disorders (Changsha), Guangzhou 510370, China.
Key Laboratory of Cognition and Personality (SWU), Ministry of Education, Chongqing 400715, China; Faculty of Psychology, Southwest University, Chongqing 400715, China; School of Management, Zunyi Medical University, Guizhou 563000, China.
Psychiatry Res. 2017 Oct;256:144-149. doi: 10.1016/j.psychres.2017.06.021. Epub 2017 Jun 15.
Schizophrenia is considered a complex illness with multiple cognitive dysfunctions, including a deficit in visual processing. However, whether the deficiency of visual processing in schizophrenia is general across stimuli or stimulus-specific remains the subject of debate. In the current study, eighteen first-episode schizophrenic patients and eighteen healthy controls participated in three visual search tasks in which they were asked to search a specific target of a triangle, face identity or facial affect. The results showed that, compared to healthy controls, the accuracies for face identity and facial affect searches were significantly lower in schizophrenic patients, while the performance of the triangle search was the same. Furthermore, the accuracy of the facial affect search was negatively correlated to negative symptoms in schizophrenia. These results revealed a face-related deficit in schizophrenia and suggest that visual processing deficits in schizophrenia were stimuli-specific.
精神分裂症被认为是一种复杂的疾病,存在多种认知功能障碍,包括视觉处理缺陷。然而,精神分裂症患者的视觉处理缺陷是否在所有刺激物上都存在,还是在特定刺激物上存在,这仍然存在争议。在本研究中,18 名首发精神分裂症患者和 18 名健康对照者参与了三项视觉搜索任务,要求他们搜索三角形、面孔身份或面部表情的特定目标。结果表明,与健康对照组相比,精神分裂症患者对面孔身份和面部表情搜索的准确性显著降低,而三角形搜索的表现则相同。此外,面部表情搜索的准确性与精神分裂症中的阴性症状呈负相关。这些结果揭示了精神分裂症中与面孔相关的缺陷,并表明精神分裂症中的视觉处理缺陷是特定于刺激的。