Cullen Aravena Roberto, Cullen Aravena Daniella, Velasco Margarita Jo, Queirolo González Alejandra, Requena Luis
Interno de Medicina, Universidad de los Andes, Santiago, Chile.
Dermatol Online J. 2017 Jun 15;23(6):13030/qt3hm3z850.
In most cases, cutaneous metastases develop after the diagnosis of the primary internal malignancy has been established, but sometimes they can be discovered earlier or simultaneously. We describe a case of a 90-year-old woman who presented to the emergency room in poor general condition, with cutaneous lesions characterized by hot, infiltrated, violaceous and erythematous plaques involving the left chest wall. The clinical and histopathological findings were consistent with the recently described variant of inflammatory cutaneous metastatic carcinoma named carcinoma hemorrhagiectoides. Microscopic examination demonstrated extensive infiltration of the dermis by tumor cells as well as intralymphatic involvement by neoplastic cells. This is a very rare presentation of cutaneous metastasis from breast cancer.
在大多数情况下,皮肤转移瘤是在原发性内脏恶性肿瘤确诊后出现的,但有时也可能更早或同时被发现。我们报告一例90岁女性患者,她因全身状况不佳被送往急诊室,其皮肤病变表现为累及左胸壁的热、浸润性、紫红色和红斑性斑块。临床和组织病理学检查结果与最近描述的炎性皮肤转移癌的一种变异型——出血性癌相符。显微镜检查显示肿瘤细胞广泛浸润真皮,且肿瘤细胞累及淋巴管。这是乳腺癌皮肤转移的一种非常罕见的表现。