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下肢前部的生殖器外大疱性硬化性苔藓:1例报告及文献复习

Extragenital bullous lichen sclerosus on the anterior lower extremities: report of a case and literature review.

作者信息

Arnold Nichelle, Manway Mitch, Stephenson Sean, Lipkin Howard

机构信息

Michigan State University Dermatology Residency Program, Beaumont Hospital Farmington Hills, Farmington Hills, Michigan.

出版信息

Dermatol Online J. 2017 Jun 15;23(6):13030/qt8dn3p7kv.

Abstract

Lichen sclerosus (LS) is a benign, chronic, inflammatory skin disease with a predilection for the anogenital region in women. Although males can also be affected, the ratio of female to male incidence has been reported to be as high as 6-10:1 and possesses a bimodal age distribution of pre-pubertal girls and postmenopausal women [1, 2]. Affected skin usually demonstrates polygonal papules that coalesce into porcelain white plaques and can be associated with edema, telangiectasias, and comedo-like plug formation [3]. Lichen sclerosus can be debilitating for some patients causing significant pruritus, pain, dysuria, and dyspareunia [4]. Rarely, lichen sclerosus appears in various extragenital areas, although most cases are relatively asymptomatic [3]. Even more uncommonly, as displayed in this case report of a 69-year-old woman, LS can present extragenitally with a bullous or hemorrhagic appearance [5].

摘要

硬化性苔藓(LS)是一种良性、慢性炎症性皮肤病,好发于女性的肛门生殖器区域。虽然男性也可受累,但据报道女性与男性的发病率之比高达6 - 10:1,且具有青春期前女孩和绝经后女性两个发病高峰的年龄分布[1, 2]。受累皮肤通常表现为多边形丘疹,融合成瓷白色斑块,并可伴有水肿、毛细血管扩张和粉刺样栓子形成[3]。硬化性苔藓可使一些患者衰弱,导致严重瘙痒、疼痛、排尿困难和性交困难[4]。虽然大多数病例相对无症状,但硬化性苔藓很少出现在各种生殖器外区域[3]。更罕见的是,如本病例报告中的一名69岁女性所示,硬化性苔藓可在生殖器外表现为大疱性或出血性外观[5]。

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