Eljazouly Madiha, Agharbi Fatima Zahra, Alj Maha, Oqbani Kenza, Chiheb Soumiya
Dermatology Unit, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR.
Pathology Unit, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR.
Cureus. 2021 Nov 30;13(11):e20047. doi: 10.7759/cureus.20047. eCollection 2021 Nov.
Lichen planus pigmentosus (LPP), an uncommon variant of lichen planus (LP), is characterized by diffuse hyperpigmented dark brown macules in sun-exposed areas. We report an unusual case of LPP with a blaschkoid distribution in an area of radiotherapy for breast cancer. This description is rarely reported. Its pathogeny is poorly understood and suggests an embryological origin by genetic mosaicism and also discusses the immunomodulatory role of radiotherapy in the disease.
色素性扁平苔藓(LPP)是扁平苔藓(LP)的一种罕见变体,其特征为暴露于阳光下的部位出现弥漫性色素沉着的深褐色斑疹。我们报告了一例罕见的色素性扁平苔藓病例,其在乳腺癌放疗区域呈线状分布。这种情况鲜有报道。其发病机制尚不清楚,提示可能起源于胚胎期的基因镶嵌现象,同时也探讨了放疗在该疾病中的免疫调节作用。