Susanti Ari Indra, Sahiratmadja Edhyana, Winarno Gatot, Sugianli Adhi Kristianto, Susanto Herman, Panigoro Ramdan
Program Study of Midwifery, Division of Maternal and Child Health, Department of Public Health, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
Anemia. 2017;2017:6935648. doi: 10.1155/2017/6935648. Epub 2017 May 29.
Low hemoglobin (Hb) or anemia is common among pregnant women in developing countries which may cause adverse pregnancy outcomes and maternal deaths. Our study aimed to assess Hb level measured by midwives in primary health care facility at rural area of Jatinangor, Indonesia, and to explore whether the anemia was due to iron deficiency (IDA) or -thalassemia trait (-TT). Pregnant women ( = 105) had finger prick test for Hb level during a regular antenatal care examination from October to November 2016. Hb level by finger prick test was compared with venous blood, measured by complete blood count (CBC). Indices including MCV and MCH and indices of Shine & Lal, Mentzer, Srivastava, Engels & Frase, Ehsani, and Sirdah were analyzed to differentiate anemia due to IDA and anemia due to suspect -TT. HbA2 was measured to confirm -TT. Anemic pregnant women were found in 86.7% by finger prick test compared to 21.9% ( = 23) by CBC. The prevalence of -TT in our study was 5.7%. Hb measurement among pregnant women in low resource area is highly important; however, finger prick test in this study showed a high frequency of anemia which may lead to iron oversupplementation. A standard CBC is encouraged; MCV and MCH would help midwives to identify -TT.
血红蛋白（Hb）水平低或贫血在发展中国家的孕妇中很常见，这可能会导致不良妊娠结局和孕产妇死亡。我们的研究旨在评估印度尼西亚贾蒂南戈尔农村地区初级卫生保健机构中助产士测量的Hb水平，并探讨贫血是否由缺铁性贫血（IDA）或β地中海贫血特征（β-TT）引起。2016年10月至11月期间，105名孕妇在常规产前检查时进行了手指采血检测Hb水平。将手指采血检测的Hb水平与通过全血细胞计数（CBC）测量的静脉血进行比较。分析包括平均红细胞体积（MCV）和平均红细胞血红蛋白含量（MCH）以及Shine & Lal、Mentzer、Srivastava、Engels & Frase、Ehsani和Sirdah指数，以区分IDA所致贫血和疑似β-TT所致贫血。测量HbA2以确诊β-TT。通过手指采血检测发现86.7%的孕妇贫血，而通过CBC检测为21.9%（23例）。我们研究中β-TT的患病率为5.7%。在资源匮乏地区对孕妇进行Hb测量非常重要；然而，本研究中的手指采血检测显示贫血发生率很高，这可能导致铁补充过量。建议采用标准的CBC检测；MCV和MCH将有助于助产士识别β-TT。
