Simonen O, Laitinen O
Lancet. 1985 Aug 24;2(8452):432-4. doi: 10.1016/s0140-6736(85)92748-5.
The incidence of femoral-neck fracture was compared in 2 Finnish towns of similar economic structure, Kuopio and Jyväskylä. Kuopio has fluoridated its drinking-water since 1959, whereas Jyväskylä has only trace amounts of fluoride in its drinking-water. The incidence of bone fragility (measured as femoral-neck fractures) was found to be significantly less in Kuopio than in Jyväskylä. This finding seems to be associated with a fluoride content of 1 mg/l in the drinking-water of Kuopio.
在芬兰两个经济结构相似的城镇库奥皮奥和于韦斯屈莱,对股骨颈骨折的发病率进行了比较。自1959年以来,库奥皮奥的饮用水已进行氟化处理,而于韦斯屈莱的饮用水中只有微量的氟化物。结果发现,库奥皮奥的骨脆性(以股骨颈骨折衡量)发病率明显低于于韦斯屈莱。这一发现似乎与库奥皮奥饮用水中1毫克/升的氟含量有关。