水氟化对年轻女性骨矿物质密度的影响。
The effect of water fluoridation on the bone mineral density of young women.
作者信息
Arnold C M, Bailey D A, Faulkner R A, McKay H A, McCulloch R G
机构信息
College of Physical Education, University of Saskatchewan, Saskatoon.
出版信息
Can J Public Health. 1997 Nov-Dec;88(6):388-91. doi: 10.1007/BF03403912.
INTRODUCTION
Osteogenic effects of therapeutic fluoride have been reported; however, the impact of exposure to low level water fluoridation on bone density is not clear. We investigated the effect of long-term exposure to fluoridated water from growth to young adulthood on bone mineral density (BMD).
METHODS
BMD was measured in 24 healthy women from Regina (fluoride 0.1 mg/L) and 33 from Saskatoon (fluoride 1.0 mg/L), with no differences between groups for height, weight, lifestyle or dietary factors.
RESULTS
Saskatoon women had significantly higher mean BMD at total anterior-posterior lumbar spine (APS) and estimated volumetric 1.3 (VLS), with no difference at total body (TB) or proximal femur (PF).
CONCLUSION
Exposure to water fluoridation during the growing years may have a positive impact on axial spine bone density in young women.
引言
已有报道称治疗性氟化物具有成骨作用；然而，长期接触低水平的水氟化对骨密度的影响尚不清楚。我们研究了从生长到成年早期长期接触氟化水对骨矿物质密度（BMD）的影响。
方法
对来自里贾纳的24名健康女性（氟化物含量为0.1毫克/升）和来自萨斯卡通的33名健康女性（氟化物含量为1.0毫克/升）进行骨密度测量，两组在身高、体重、生活方式或饮食因素方面无差异。
结果
萨斯卡通的女性在腰椎前后位（APS）和估计的体积1.3（VLS）处的平均骨密度显著更高，在全身（TB）或股骨近端（PF）处无差异。
结论
生长期间接触水氟化可能对年轻女性的轴向脊柱骨密度有积极影响。
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