Arnold C M, Bailey D A, Faulkner R A, McKay H A, McCulloch R G
College of Physical Education, University of Saskatchewan, Saskatoon.
Can J Public Health. 1997 Nov-Dec;88(6):388-91. doi: 10.1007/BF03403912.
Osteogenic effects of therapeutic fluoride have been reported; however, the impact of exposure to low level water fluoridation on bone density is not clear. We investigated the effect of long-term exposure to fluoridated water from growth to young adulthood on bone mineral density (BMD).
BMD was measured in 24 healthy women from Regina (fluoride 0.1 mg/L) and 33 from Saskatoon (fluoride 1.0 mg/L), with no differences between groups for height, weight, lifestyle or dietary factors.
Saskatoon women had significantly higher mean BMD at total anterior-posterior lumbar spine (APS) and estimated volumetric 1.3 (VLS), with no difference at total body (TB) or proximal femur (PF).
Exposure to water fluoridation during the growing years may have a positive impact on axial spine bone density in young women.
已有报道称治疗性氟化物具有成骨作用；然而，长期接触低水平的水氟化对骨密度的影响尚不清楚。我们研究了从生长到成年早期长期接触氟化水对骨矿物质密度（BMD）的影响。
对来自里贾纳的24名健康女性（氟化物含量为0.1毫克/升）和来自萨斯卡通的33名健康女性（氟化物含量为1.0毫克/升）进行骨密度测量，两组在身高、体重、生活方式或饮食因素方面无差异。
萨斯卡通的女性在腰椎前后位（APS）和估计的体积1.3（VLS）处的平均骨密度显著更高，在全身（TB）或股骨近端（PF）处无差异。
生长期间接触水氟化可能对年轻女性的轴向脊柱骨密度有积极影响。
