Suarez-Almazor M E, Flowerdew G, Saunders L D, Soskolne C L, Russell A S
Department of Medicine, University of Alberta, Edmonton, Canada.
Am J Public Health. 1993 May;83(5):689-93. doi: 10.2105/ajph.83.5.689.
The purpose of this study was to compare hip fracture hospitalization rates between a fluoridated and a non-fluoridated community in Alberta, Canada: Edmonton, which has had fluoridated drinking water since 1967, and Calgary, which considered fluoridation in 1991 but is currently revising this decision.
Case subjects were all individuals aged 45 years or older residing in Edmonton or Calgary who were admitted to hospitals in Alberta between January 1, 1981, and December 31, 1987, and who had a discharge diagnosis of hip fracture. Edmonton rates were compared with Calgary rates, with adjustment for age and sex using the Edmonton population as a standard.
The hip fracture hospitalization rate for Edmonton from 1981 through 1987 was 2.77 per 1000 person-years. The age-sex standardized rate for Calgary was 2.78 per 1000 person-years. No statistically significant difference was observed in the overall rate, and only minor differences were observed within age and sex subgroups, with the Edmonton rates being higher in males.
These findings suggest that fluoridation of drinking water has no impact, neither beneficial nor deleterious, on the risk of hip fracture.
本研究旨在比较加拿大艾伯塔省一个有氟化物社区和一个无氟化物社区的髋部骨折住院率：埃德蒙顿自1967年起就有含氟饮用水，卡尔加里在1991年考虑实施氟化，但目前正在重新审视这一决定。
病例对象为1981年1月1日至1987年12月31日期间入住艾伯塔省医院、年龄在45岁及以上、居住在埃德蒙顿或卡尔加里且出院诊断为髋部骨折的所有个体。以埃德蒙顿人口为标准，对年龄和性别进行调整后，将埃德蒙顿的发病率与卡尔加里的发病率进行比较。
1981年至1987年期间，埃德蒙顿的髋部骨折住院率为每1000人年2.77例。卡尔加里的年龄 - 性别标准化发病率为每1000人年2.78例。总体发病率未观察到统计学上的显著差异，在年龄和性别亚组中仅观察到微小差异，男性中埃德蒙顿的发病率更高。
这些发现表明，饮用水氟化对髋部骨折风险没有影响，既无益处也无害处。
