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一项关于切口疝修补的随机对照试验中,长期的肌后和腹膜内补片尺寸变化,包括文献综述。

Long-term retromuscular and intraperitoneal mesh size changes within a randomized controlled trial on incisional hernia repair, including a review of the literature.

作者信息

Rogmark P, Ekberg O, Montgomery A

机构信息

Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden.

Department of Surgery, Skåne University Hospital, 205 02, Malmö, Sweden.

出版信息

Hernia. 2017 Oct;21(5):687-696. doi: 10.1007/s10029-017-1624-9. Epub 2017 Jun 20.

DOI:10.1007/s10029-017-1624-9
PMID:28634690
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5608776/
Abstract

UNLABELLED

Purpose Ingrowth of fibroblasts in a polypropylene mesh may cause contraction and a later recurrence. We assessed mesh contraction in intraabdominal and retromuscular implantation after incisional hernia repair.

METHODS

A cohort of patients within an RCT on laparoscopic (LHR) versus open hernia repair (OHR) had their mesh borders marked with metal clips. X-ray was performed on postoperative day 1 and after 1 year. Total length, width, and dislocation were measured. A tacker fixated large-pore polypropylene mesh was used in LHR, and a retromuscular small-pore heavy-weight mesh was sutured to the midline in OHR. Patient's pain was assessed before surgery and after 1 year.

RESULTS

For analysis 37/47 patients remained: 20 LHR and 17 OHR. Hernia defect area was median 41 cm in LHR and 25 cm in OHR (p < 0.140). Implanted mesh size was 300 cm for LHR and 240 cm for OHR (p < 0.341). After 1 year the mesh area decreased by 4.4% and 0.5% in LHR and OHR, respectively (p < 0.063). Longitudinal distance decreased by 2.8% in LHR and by 2.6% in OHR (p < 0.269). Transverse distance decreased by 1.6% in LHR but increased by 3.1% in OHR (p < 0.005). Dislocation was seen in four LHR and one OHR. Two recurrent and one port-site hernia were diagnosed after LHR. Measurements between observers were identical in 58% and consensus was made in the remainder. Pain was not correlated to mesh area change.

CONCLUSIONS

Mesh contraction after 1 year is not a clinical issue for an intraperitoneal large-pore mesh or a retromuscular small-pore mesh. It is not correlated to postoperative pain.

摘要

未标记

目的 成纤维细胞在聚丙烯网片中向内生长可能导致收缩及后期复发。我们评估了切口疝修补术后腹腔内和肌后植入网片的收缩情况。

方法

一项关于腹腔镜疝修补术(LHR)与开放疝修补术(OHR)对比的随机对照试验中的一组患者,其网片边缘用金属夹标记。术后第1天和1年后进行X线检查。测量总长度、宽度和移位情况。LHR中使用了带钉固定的大孔聚丙烯网片,OHR中将肌后小孔重型网片缝合至中线。在手术前和1年后评估患者的疼痛情况。

结果

为进行分析,剩余37/47例患者:20例LHR和17例OHR。LHR中的疝缺损面积中位数为41平方厘米,OHR中为25平方厘米(p < 0.140)。LHR中植入的网片大小为300平方厘米,OHR中为240平方厘米(p < 0.341)。1年后,LHR中网片面积分别减少4.4%,OHR中减少0.5%(p < 0.063)。纵向距离LHR中减少2.8%,OHR中减少2.6%(p < 0.269)。横向距离LHR中减少1.6%,但OHR中增加3.1%(p < 0.005)。4例LHR和1例OHR出现移位。LHR后诊断出2例复发性疝和1例切口疝。观察者之间的测量结果在58%的情况下相同,其余达成共识。疼痛与网片面积变化无关。

结论

1年后网片收缩对于腹腔内大孔网片或肌后小孔网片而言并非临床问题。它与术后疼痛无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d1/5608776/0bed3c2d232f/10029_2017_1624_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d1/5608776/34fd80bfac88/10029_2017_1624_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d1/5608776/de0f057d690f/10029_2017_1624_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d1/5608776/0bed3c2d232f/10029_2017_1624_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d1/5608776/34fd80bfac88/10029_2017_1624_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d1/5608776/de0f057d690f/10029_2017_1624_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d1/5608776/0bed3c2d232f/10029_2017_1624_Fig3_HTML.jpg

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