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根据生命最初七个月的数据预测四岁时的发育缺陷。

Predicting developmental deficiencies at the age of four based on data from the first seven months of life.

作者信息

Rostad Anne Margrethe, Nyberg Per, Sivberg Bengt

机构信息

Norwegian University of Science and Technology, Trondheim, and Levanger Hospital, Levanger, Norway.

Lund University, Sweden.

出版信息

Infant Ment Health J. 2008 Nov;29(6):588-608. doi: 10.1002/imhj.20194.

DOI:10.1002/imhj.20194
PMID:28636247
Abstract

The study examines very young children with the aim of identifying precursors of developmental problems during the first 7 months of age. Information from screening and observations in the birth clinic, in the first level of health care, and from parents was collected on five different occasions. The information that was included concerning the child and family was defined as either optimal or nonoptimal. At the age of 4 years, a clinical group was identified (11.1% of the total population). Logistic regression analyses were performed to detect risk factors. Twenty-one precursors were used to create a screening questionnaire that provided useful information (sensitivity = 56.1%, specificity = 98.8%) for predicting developmental problems of the children. The contribution of sociodemographic data was significant; medical information was less significant. The highest prediction rate surprisingly was found in the moderate clinical subgroup (62.1%), compared to the group with more severe problems that had a slightly lower rate (46.7%). The conclusion of the study is that it is possible to detect infants in need of early intervention using a continuous process of observation and screening.

摘要

该研究对非常年幼的儿童进行检查,目的是识别7个月大之前发育问题的先兆。在出生诊所、一级医疗保健机构以及通过家长,在五个不同时间点收集了筛查和观察信息。收集到的有关儿童和家庭的信息被定义为最佳或非最佳。在4岁时,确定了一个临床组(占总人口的11.1%)。进行了逻辑回归分析以检测风险因素。使用21种先兆因素创建了一份筛查问卷,该问卷为预测儿童发育问题提供了有用信息(敏感性=56.1%,特异性=98.8%)。社会人口统计学数据的贡献显著;医疗信息的贡献较小。令人惊讶的是,与问题较严重、预测率略低(46.7%)的组相比,中度临床亚组的预测率最高(62.1%)。该研究的结论是,通过持续的观察和筛查过程,可以检测出需要早期干预的婴儿。

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