痤疮治疗中的抗生素耐药性。
Antibiotic Resistance in Acne Treatment.
机构信息
Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles.
Drexel University College of Medicine, Philadelphia, Pennsylvania.
出版信息
JAMA Dermatol. 2017 Aug 1;153(8):810-811. doi: 10.1001/jamadermatol.2017.1297.
CLINICAL QUESTION
What is the evidence for antibiotic resistance in acne, and how does resistance affect treatment?
BOTTOM LINE
Use of topical and systemic antibiotics for acne is associated with formation of resistance in Propionibacterium acnes and other bacteria, with clinical consequences. Guidelines recommend resistance reduction strategies including avoidance of antibiotic monotherapy, combination treatment with topical modalities, and limiting the duration of oral antibiotic use.
临床问题
痤疮中抗生素耐药的证据是什么，耐药性如何影响治疗？
要点
痤疮患者使用局部和全身用抗生素与痤疮丙酸杆菌和其他细菌耐药的形成有关，并具有临床后果。指南建议采用降低耐药性的策略，包括避免抗生素单药治疗、联合局部治疗以及限制口服抗生素的使用时间。
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