Eom Bang Wool, Kim Jeongseon, Kim Deok Hee, Kim Young-Il, Yoon Hong Man, Cho Soo-Jeong, Lee Jong Yeul, Kim Chan Gyoo, Choi Il Ju, Kim Young-Woo, Nam Byung-Ho, Ryu Keun Won
Gastric Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyang-si, Republic of Korea.
Dig Surg. 2018;35(3):220-229. doi: 10.1159/000477779. Epub 2017 Jun 22.
This study was aimed at evaluating the food intake and nutritional status of patients who underwent gastrectomy for gastric cancer based on a large-scale gastric cancer cohort.
An observational prospective cohort study for gastric cancer has been conducted since 2010. From the cohort data, we selected the data for patients who completed at least 2 days of 3-day diet diaries and who underwent subtotal gastrectomy (STG) or total gastrectomy (TG). As a control group, patients who underwent endoscopic submucosal dissection were also included. The collected diet data were converted to macro- and micronutrients using computerized software, and the nutrient intakes were compared.
Among 6,556 patients who participated in the cohort study from 2011 to 2016, 1,289 patients who completed at least 2 days of 3-day diet diaries were included in this study. During the postoperative 3-month period, body weight was significantly decreased in the and TG groups. However, there was no difference in nutrient intake among the 3 groups except vitamin D and calcium intake. Similar results were observed during the postoperative 12 months period.
Postoperative body weight loss and anemia might originate from altered absorptive function and metabolic change after gastrectomy rather than decreased nutrient intake.
本研究旨在基于一个大规模胃癌队列评估接受胃癌胃切除术患者的食物摄入量和营养状况。
自2010年以来开展了一项针对胃癌的观察性前瞻性队列研究。从队列数据中，我们选取了完成至少2天的3天饮食日记且接受了胃次全切除术（STG）或全胃切除术（TG）的患者的数据。作为对照组，还纳入了接受内镜黏膜下剥离术的患者。使用计算机软件将收集到的饮食数据转换为宏量营养素和微量营养素，并比较营养摄入量。
在2011年至2016年参与队列研究的6556例患者中，本研究纳入了1289例完成至少2天的3天饮食日记的患者。在术后3个月期间，STG组和TG组的体重显著下降。然而，除维生素D和钙摄入量外，3组之间的营养摄入量没有差异。在术后12个月期间也观察到了类似结果。
术后体重减轻和贫血可能源于胃切除术后吸收功能改变和代谢变化，而非营养摄入量减少。
