Saleh Parviz, Sadeghpour Alireza, Mirza-Aghazadeh-Attari Mohammad, Hatampour Mohammad, Naghavi-Behzad Mohammad, Tabrizi Aidin
Chronic Renal Disease Referral Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Orthopedic Surgery, Tabriz University of Medical Sciences, Tabriz, Iran.
Tanaffos. 2017;16(1):40-45.
Pneumonia is a common disease and is more prevalent among children and the elderly. Zinc (Zn) is an essential substance for the human body and plays an important role in regulating the immune system. Studies have shown a possible relation between the Zn plasma levels and pneumonia.
In a cross-sectional study, 100 patients with pneumonia, who were referred to the Educational-Medical Centers of Tabriz University of Medical Sciences, were included in the study. The plasma levels of Zn of all patients were measured. The patients were divided into two groups of normal and low plasma levels of Zn. The severity and clinical course of pneumonia, including the durations of fever, tachycardia, and tachypnea were evaluated and compared between the two groups.
The plasma levels of Zn were normal in 56 patients and low in 44 patients. The mean duration of fever, tachycardia, and tachypnea in the group with normal plasma levels of Zn were 1.58±0.68, 2.04±0.81, and 2.78±0.84 days, respectively; and those in the group with decreased Zn plasma levels were 1.72±0.70, 2.18±0.90, and 2.97±0.91 days, respectively. There were no statistically significant differences between the two groups (P>0.05). However, the incidence of severe pneumonia was significantly less in the group with normal Zn plasma levels (P=0.001).
Based on the findings of the present study, there was no statistically significant relationship between the plasma levels of Zn and the clinical course of pneumonia. However, Zn lowered the incidence of severe pneumonia.
肺炎是一种常见疾病，在儿童和老年人中更为普遍。锌（Zn）是人体必需的物质，在调节免疫系统中起重要作用。研究表明血浆锌水平与肺炎之间可能存在关联。
在一项横断面研究中，纳入了100例转诊至大不里士医科大学教育医疗中心的肺炎患者。测量了所有患者的血浆锌水平。患者被分为血浆锌水平正常和低两组。评估并比较了两组肺炎的严重程度和临床病程，包括发热、心动过速和呼吸急促的持续时间。
56例患者血浆锌水平正常，44例患者血浆锌水平低。血浆锌水平正常组的发热、心动过速和呼吸急促的平均持续时间分别为1.58±0.68天、2.04±0.81天和2.78±0.84天；血浆锌水平降低组的分别为1.72±0.70天、2.18±0.90天和2.97±0.91天。两组之间无统计学显著差异（P>0.05）。然而，血浆锌水平正常组的重症肺炎发生率显著较低（P=0.001）。
根据本研究结果，血浆锌水平与肺炎临床病程之间无统计学显著关系。然而，锌降低了重症肺炎的发生率。
