Arıca Seçil, Arıca Vefik, Dag Hüseyin, Kaya Ayşen, Hatipoglu Sami, Fenercioglu Aysen, Karatekin Güner
Int J Clin Exp Med. 2011;4(3):227-33. Epub 2011 Sep 15.
We have planned to study the relationship between zinc (Zn) plasma levels, as well as pneumonia criteria, and zinc in healthy children younger than 2 years of age compared to pediatric patients diagnosed with pneumonia and admitted to a hospital.
The study enrolled 25 patients of 0-24 months referring to our hospital's pediatric clinic, who were then diagnosed with bronchopneumonia based on the World Health Organization diagnostic criteria and admitted to suckling children clinic due to inability to receive out-patient treatment, and 10 healthy children of the same age group, whose physical examinations revealed no pathological findings.
There was no difference between the groups in terms of age and gender distribution (p> 0.05). The control group included in the study showed a significantly higher mean duration of breast milk intake compared to the patient groups (p<0.001). WBC values obtained from the patient group was significantly higher than that of the control group (p<0.001). Zn and iron (Fe) values as determined in the control group enrolled in the study were significantly higher compared to the patient group (p<0.01). Mean total protein in the control group was found to be significantly higher versus that of the patient groups (p<0.05). With regard to the r values of correlation coefficients of the subjects enrolled in the study, a slightly positive correlation was observed between Zn levels and iron levels (r=0.457).
It was concluded that infections, particularly pneumonia, which present a serious issue both in our country and developing countries, may be developed more commonly among children with zinc deficiency.
我们计划研究2岁以下健康儿童与诊断为肺炎并住院的儿科患者的血浆锌（Zn）水平、肺炎标准以及锌之间的关系。
该研究纳入了25名0至24个月转诊至我院儿科门诊的患者，这些患者随后根据世界卫生组织诊断标准被诊断为支气管肺炎，并因无法接受门诊治疗而入住婴儿诊所，以及10名同年龄组的健康儿童，他们的体格检查未发现病理结果。
两组在年龄和性别分布方面无差异（p>0.05）。研究中的对照组与患者组相比，母乳喂养的平均持续时间显著更长（p<0.001）。患者组获得的白细胞值显著高于对照组（p<0.001）。研究中纳入的对照组测定的锌和铁（Fe）值显著高于患者组（p<0.01）。发现对照组的平均总蛋白显著高于患者组（p<0.05）。关于研究中纳入受试者的相关系数r值，锌水平与铁水平之间观察到轻微正相关（r=0.457）。
得出的结论是，感染，尤其是肺炎，在我国和发展中国家都是一个严重问题，可能在缺锌儿童中更常见。
