Mohammadi Hamzeh, Farhang Dehghan Somayeh, Golbabaei Farideh, Roshani Saman, Pakzad Reza, Foroughi Parvin, Hajizadeh Roohalah
Department of Occupational Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Department of Occupational Health, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Tanaffos. 2017;16(1):60-67.
This study aimed to investigate the pulmonary functions of silica-exposed workers and their health-related quality of life in an insulator manufacturing industry.
In this cross-sectional study, participants selected from the manufacturing unit (n = 127) constituted the exposed group and those from the administrative department (n = 30) constituted the unexposed group. All subjects were evaluated using personal air sampling of crystalline silica, pulmonary function tests, and a quality of life questionnaire (36-item short form health survey [SF-36]).
The mean (SD) concentrations of crystalline silica were 0.507 (0.23) mg/m and 0.0116 (0.008) mg/m for the exposed and unexposed groups, respectively. All the pulmonary function indices and all the physical and mental health domains of the workers were significantly lower than those of the administrative clerks (p < 0.05). The silica concentration did not significantly correlate with the quality of life components and all the pulmonary function indices (p > 0.05), except for forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) (p < 0.05).
In conclusion, the workers exposed to higher levels of crystalline silica had lower values of pulmonary function indices and lower health-related quality of life; however, further follow-up studies are needed to confirm these findings.
本研究旨在调查绝缘材料制造行业中接触二氧化硅的工人的肺功能及其与健康相关的生活质量。
在这项横断面研究中,从制造部门选取的参与者(n = 127)构成暴露组,从行政部门选取的参与者(n = 30)构成非暴露组。所有受试者均通过对结晶二氧化硅进行个人空气采样、肺功能测试以及生活质量问卷(36项简短健康调查问卷[SF - 36])进行评估。
暴露组和非暴露组的结晶二氧化硅平均(标准差)浓度分别为0.507(0.23)mg/m³和0.0116(0.008)mg/m³。工人的所有肺功能指标以及所有身体和心理健康领域均显著低于行政职员(p < 0.05)。二氧化硅浓度与生活质量成分以及所有肺功能指标均无显著相关性(p > 0.05),但用力肺活量(FVC)和一秒用力呼气量(FEV1)除外(p < 0.05)。
总之,接触较高水平结晶二氧化硅的工人肺功能指标值较低且与健康相关的生活质量较低;然而,需要进一步的随访研究来证实这些发现。