[Effects of p-phenylenediamine on lung function and health-related quality of life of workers].

To study the effects -phenylenediamine (PPD) on lung function and health-related quality of life of occupational exposed workers. This study was based on data from a company that produce hair dye containing PPD in China. Workers who exposed to PPD were selected as the study group, and workers un-exposed to PPD were selected as the control group. Questionnaires on health-related quality of life of workers using the 36-item Short Form Health Survey (SF-36) . Occupational health examination assessment results were tested in Taizhou Cancer Hospital. The lung function test includes forced vital capacity (FVC) , forced expiratory volume in one second (FEV(1.0)) , and ratio of FEV(1.0) to FVC (FEV(1.0)/FVC) . The difference in systolic blood pressure between the PPD exposed group and the control group was statistically significant (<0.05) . FVC, FEV(1.0), and FEV(1.0)/FVC of the lung function indexes in the exposed group were lower than those in the control group (<0.05) . In the health-related quality of life, body pain (=0.002) , general health (=0.029) , vitality (=0.038) , and mental health (=0.003) were lower in the exposed group than in the control group. Occupational exposed to PPD may induce hazard to the workers'lung function and may cause detrimental effect on workers' health-related quality of life.