Oiwa Hiroshi, Yamabe Toru, Kawashima Masanori, Maetani Yuta, Agari Dai, Yamawaki Takemori, Sugiyama Eiji
Department of Rheumatology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.
Department of Internal Medicine, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.
Eur J Rheumatol. 2017 Jun;4(2):148-150. doi: 10.5152/eurjrheum.2017.160099. Epub 2017 Jun 1.
Lupus myelitis (LM) is a rare but serious complication of systemic lupus erythematosus (SLE). In 2009, Birnbaum et al. suggested that LM could be classified into two subtypes, namely gray and white matter myelitis, based on neurological examination findings. Here we describe three cases of this disorder, one with signs of white matter dysfunction and two with signs of gray matter dysfunction. We discuss the potential role of autoantibodies in the development of LM.
狼疮性脊髓炎(LM)是系统性红斑狼疮(SLE)一种罕见但严重的并发症。2009年,Birnbaum等人提出,根据神经学检查结果,LM可分为两种亚型,即灰质和白质脊髓炎。在此,我们描述了三例该疾病,一例有白质功能障碍体征,两例有灰质功能障碍体征。我们讨论了自身抗体在LM发病过程中的潜在作用。