Wellenstein David J, de Witt Joey K, Schutte Henrieke W, Honings Jimmie, van den Hoogen Frank J A, Marres Henri A M, Takes Robert P, van den Broek Guido B
Department of Otorhinolaryngology and Head and Neck Surgery, Radboud University Medical Center, Philips van Leydenlaan 15, 6500 HB, Nijmegen, The Netherlands.
Department of Surgery, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Eur Arch Otorhinolaryngol. 2017 Sep;274(9):3471-3476. doi: 10.1007/s00405-017-4647-z. Epub 2017 Jun 21.
Recent advancements in transnasal endoscopy enable a shift in diagnostic workup of lesions in the pharynx and larynx, from an examination with biopsy under general anesthesia to an office-based examination with flexible endoscopic biopsy under topical anesthesia. Procedural complications were evaluated to assess the safety of office-based flexible endoscopic biopsy in patients with benign and malignant laryngopharyngeal lesions. Patients who underwent flexible endoscopic biopsy from 2012 to 2016 were evaluated retrospectively. Complications were classified using the Clavien-Dindo classification of surgical complications. A total of 201 flexible endoscopic biopsies were performed in 187 patients. Two Clavien-Dindo grade I (laryngospasm and anterior epistaxis), one grade II (laryngeal bleeding), and one grade IIIb (laryngeal edema) complication were observed. The first complication was self-limiting and the other three required an intervention. All patients fully recovered without sequelae. Flexible endoscopic biopsy appears to be a safe office-based procedure for the diagnosis of benign and malignant laryngopharyngeal lesions.
经鼻内镜检查的最新进展使得咽喉部病变的诊断检查方式发生了转变，从全身麻醉下活检检查转变为局部麻醉下使用软性内镜活检的门诊检查。对手术并发症进行评估，以评估门诊软性内镜活检对喉咽良性和恶性病变患者的安全性。对2012年至2016年接受软性内镜活检的患者进行回顾性评估。使用Clavien-Dindo手术并发症分类法对并发症进行分类。187例患者共进行了201次软性内镜活检。观察到2例Clavien-Dindo I级并发症（喉痉挛和鼻出血）、1例II级并发症（喉部出血）和1例IIIb级并发症（喉部水肿）。第一例并发症为自限性，其他三例需要干预。所有患者均完全康复，无后遗症。软性内镜活检似乎是一种安全的门诊检查方法，可用于诊断喉咽良性和恶性病变。
