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纤维软性喉镜活检在耳鼻喉科疑似病变中的诊断价值

Diagnostic Usefulness of Flexible Fibroscopy Biopsy in Suspected Lesions of the Otolaryngological Area.

作者信息

Sánchez Tudela Alberto Tomás, Valido Quintana Mercedes, Colina Etala Carlos, Díaz Rodríguez Débora, Miranda Fandiño Sergio, Benítez Del Rosario Jesús Javier

机构信息

Department of Otorhinolaryngology, Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, Spain.

出版信息

Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):5440-5444. doi: 10.1007/s12070-021-02745-z. Epub 2021 Jul 11.

Abstract

The efficiency in the management of patients with suspected malignant lesions represents the main objective of the oncology of head and neck. Flexible nasopahyngolaryngoscopy with working channel allows to quickly and safely assess and obtain histological samples of this type of lesion. Our objective is to describe the usefulness of this technique in lesions suggestive of malignancy in terms of efficiency, sensitivity and specificity. A retrospective study was carried out over a period of time from December 2014 to December 2019, including patients biopsied with flexible fibroscopy of lesions of debut suspected of malignancy. Here we assess the location of the lesion, the histological results, the diagnostic time and the epidemiological variables. 104 patients were included in the study. More than half of the lesions, 55.2% (57), were located in the larynx; 57.7% (60) resulted positive for malignancy in the flexible fiberscope biopsy; 19.2% (20) were taken to the operating room to get biopsied under general anesthesia resulting in 7.4% (14) positive for malignancy, which shows a sensitivity of the test of 81%. In our sample, a diagnostic time of 15 days was obtained. Considering our results, the few complications and the revised literature, flexible fiberscope biopsy with working channel is an efficient procedure for the management of oncological patients of head and neck.

摘要

对疑似恶性病变患者的管理效率是头颈肿瘤学的主要目标。带有工作通道的可弯曲鼻咽喉镜检查能够快速且安全地评估此类病变并获取组织学样本。我们的目的是从效率、敏感性和特异性方面描述该技术在疑似恶性病变中的作用。我们进行了一项回顾性研究,研究时间跨度为2014年12月至2019年12月,纳入了因初次疑似恶性病变而接受可弯曲纤维镜活检的患者。在此我们评估病变的位置、组织学结果、诊断时间以及流行病学变量。该研究纳入了104例患者。超过半数的病变(55.2%,即57个)位于喉部;在可弯曲纤维镜活检中,57.7%(60个)的病变结果为恶性阳性;19.2%(20个)的病变被送去手术室在全身麻醉下进行活检,其中7.4%(14个)为恶性阳性,这表明该检查的敏感性为81%。在我们的样本中,诊断时间为15天。考虑到我们的结果、较少的并发症以及查阅的文献,带有工作通道的可弯曲纤维镜活检是管理头颈肿瘤患者的一种有效方法。

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