Endo Satoru, Sato Hitoshi, Shimazaki Takuto, Nakajima Erika, Kotani Kei, Suda Mitsuru, Hamano Tsuyoshi, Kajimoto Tsuyoshi, Tanaka Kenichi, Hoshi Masaharu
Quantum Energy Applications, Graduate School of Engineering, Hiroshima University, 1-4-1 Kagamiyama, Higashi-Hiroshima, 739-8527, Japan.
Radiological Sciences, Ibaraki Prefectural University of Health Science, 4669-2 Ami, Ami-machi, Inashiki-Gun, Ibaraki, 300-0394, Japan.
Radiat Environ Biophys. 2017 Aug;56(3):269-276. doi: 10.1007/s00411-017-0700-y. Epub 2017 Jun 21.
An LBO (LiBO) walled ionization chamber was designed to monitor the epithermal neutron fluence in boron neutron capture therapy clinical irradiation. The thermal and epithermal neutron sensitivities of the device were evaluated using accelerator neutrons from the Be(d, n) reaction at a deuteron energy of 4 MeV (4 MeV d-Be neutrons). The response of the chamber in terms of the electric charge induced in the LBO chamber was compared with the thermal and epithermal neutron fluences measured using the gold-foil activation method. The thermal and epithermal neutron sensitivities obtained were expressed in units of pC cm, i.e., from the chamber response divided by neutron fluence (cm). The measured LBO chamber sensitivities were 2.23 × 10 ± 0.34 × 10 (pC cm) for thermal neutrons and 2.00 × 10 ± 0.12 × 10 (pC cm) for epithermal neutrons. This shows that the LBO chamber is sufficiently sensitive to epithermal neutrons to be useful for epithermal neutron monitoring in BNCT irradiation.
设计了一种锂硼（LiBO）壁电离室，用于监测硼中子俘获疗法临床照射中的超热中子注量。使用来自4兆电子伏特氘核能量下铍（d，n）反应产生的加速器中子，评估了该装置的热中子和超热中子灵敏度（4兆电子伏特氘 - 铍中子）。将电离室在锂硼（LiBO）室中感应的电荷响应与使用金箔活化法测量的热中子和超热中子注量进行了比较。获得的热中子和超热中子灵敏度以皮库仑每平方厘米（pC/cm）为单位表示，即通过电离室响应除以中子注量（/cm）得到。测量得到的锂硼（LiBO）室对热中子的灵敏度为2.23×10±0.34×10（pC/cm），对超热中子的灵敏度为2.00×10±0.12×10（pC/cm）。这表明锂硼（LiBO）室对超热中子具有足够的灵敏度，可用于硼中子俘获疗法照射中的超热中子监测。
