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妊娠期甲状腺癌的处理方法。

Approach to thyroid carcinoma in pregnancy.

作者信息

Modesti Cristina, Aceto Paola, Masini Lucia, Lombardi Celestino Pio, Bellantone Rocco, Sollazzi Liliana

机构信息

Department of Anesthesia and Intensive Care, Agostino Gemelli Hospital, Catholic University of the Sacred Heart, Rome, Italy.

Department of Obstetrics and Gynecology, Agostino Gemelli Hospital, Catholic University of the Sacred Heart, Rome, Italy.

出版信息

Updates Surg. 2017 Jun;69(2):261-265. doi: 10.1007/s13304-017-0476-2. Epub 2017 Jun 22.

Abstract

Thyroid carcinoma is the first cancer found in general population and the second diagnosed during pregnancy following the breast one. Diagnostic and therapeutic approaches to thyroid malignancy in pregnant women pose several and serious issues to the physicians. Even if there is no consensus about the surgical treatment of thyroid carcinomas during pregnancy, a large number of women undergo surgery over the world. The best surgical and anesthesiological treatment should be chosen after reaching a consensus between surgeons, anesthesiologists, obstetrics, and the patients. From 2000 to 2016, 18 pregnant patients underwent thyroidectomy under local anesthesia (cervical plexus block) combined with conscious sedation using benzodiazepines and opiates with ultrashort duration of action. Our 15-year experience on the thyroidectomies performed using the cervical plexus block combined with conscious sedation confirms that this combined technique offers a safe chance to defeat cancer also during pregnancy. Application of hypnosis could be an interesting alternative approach to pharmacological sedation in patients who would avoid intravenous drugs.

摘要

甲状腺癌是普通人群中发现的首例癌症,是孕期继乳腺癌之后第二例被诊断出的癌症。孕妇甲状腺恶性肿瘤的诊断和治疗方法给医生带来了诸多严重问题。尽管对于孕期甲状腺癌的手术治疗尚无共识,但全球仍有大量女性接受手术。外科医生、麻醉医生、产科医生和患者之间达成共识后,应选择最佳的手术和麻醉治疗方案。2000年至2016年期间,18名孕妇在局部麻醉(颈丛阻滞)联合使用苯二氮䓬类药物和超短效作用的阿片类药物进行清醒镇静的情况下接受了甲状腺切除术。我们15年来使用颈丛阻滞联合清醒镇静进行甲状腺切除术的经验证实,这种联合技术也为孕期战胜癌症提供了安全的机会。对于那些避免使用静脉药物的患者,催眠应用可能是一种有趣的替代药物镇静的方法。

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