钯催化2-苯基吡啶与碘代烷烃的C-H烷基化反应。

Palladium-catalyzed C-H alkylation of 2-phenylpyridines with alkyl iodides.

作者信息

Wang Xiaoling, Ji Xiaoming, Shao Changdong, Zhang Yu, Zhang Yanghui

机构信息

School of Chemical Science and Engineering, and Shanghai Key Lab of Chemical Assessment and Sustainability, Tongji University, 1239 Siping Road, Shanghai, 200092, P. R. China.

出版信息

Org Biomol Chem. 2017 Jul 5;15(26):5616-5624. doi: 10.1039/c7ob01232b.

DOI:10.1039/c7ob01232b

PMID:28639643

Abstract

Palladium-catalyzed C-H alkylation reaction of 2-phenylpyridines with alkyl iodides has been successfully developed. The palladacycles obtained from 2-phenylpyridines should act as the key intermediates in the alkylation reaction.

摘要

已成功开发出钯催化的2-苯基吡啶与碘代烷的C-H烷基化反应。由2-苯基吡啶得到的钯环化合物应作为烷基化反应中的关键中间体。