Kosinski Christophe, Jornayvaz François R
Service d'endocrinologie, diabétologie et métabolisme, CHUV, 1011 Lausanne.
Service d'endocrinologie, diabétologie, hypertension et nutrition, HUG, 1211 Genève 14.
Rev Med Suisse. 2017 May 31;13(565):1145-1147.
The treatment of obesity and cardiovascular diseases is one of the most difficult and important challenges nowadays. Weight loss is frequently offered and aimed at improving some of the components of the metabolic syndrome. Among various diets, carbohydrate restriction is popular, specifically ketogenic diets, which are very low in carbohydrates and usually high in fats and /or proteins. Results are controversial, but some benefits such as weight loss and improved glycemic control have been described. Nevertheless, these effects seem to be limited in time. Moreover, these diets are not totally safe and can be associated with some adverse events such as the development of nonalcoholic fatty liver disease. The aim of this review is to discuss the role of ketogenic diets on different cardiovascular risk factors based on available evidence.
肥胖症和心血管疾病的治疗是当今最困难且重要的挑战之一。减重常常是治疗手段且旨在改善代谢综合征的某些组成部分。在各种饮食方案中，碳水化合物限制饮食很受欢迎，特别是生酮饮食，其碳水化合物含量极低，脂肪和/或蛋白质含量通常较高。结果存在争议，但已描述了一些益处，如体重减轻和血糖控制改善。然而，这些效果似乎在时间上是有限的。此外，这些饮食并不完全安全，可能与一些不良事件相关，如非酒精性脂肪性肝病的发生。本综述的目的是基于现有证据探讨生酮饮食对不同心血管危险因素的作用。
