Kozuharova Ekaterina, Matkowski Adam, Woźniak Dorota, Simeonova Rumiana, Naychov Zheko, Malainer Clemens, Mocan Andrei, Nabavi Seyed M, Atanasov Atanas G
Department of Pharmacognosy, Faculty of Pharmacy, Medical University of SofiaSofia, Bulgaria.
Department of Pharmaceutical Biology with Botanical Garden of Medicinal PlantsMedical University of Wroclaw, Poland.
Front Pharmacol. 2017 Jun 8;8:333. doi: 10.3389/fphar.2017.00333. eCollection 2017.
L. (Fabaceae) is a shrub native to North America which has been cultivated mainly for its ornamental features, honey plant value and protective properties against soil erosion. It is registered amongst the most noxious invasive species in Europe. However, a growing body of scientific literature also points to the therapeutic potential of its chemical constituents. Due to the fact that is an aggressive invasive species, it can provide an abundant and cheap resource of plant chemical constituents which can be utilized for therapeutic purposes. Additionally, exploitation of the biomass for medicinal use might contribute to relieving the destructive impact of this species on natural habitats. The aim of this review is to provide a comprehensive summary and systematize the state-of-the-art in the knowledge of the phytochemical composition and the potential of in disease treatment and prevention, with especial emphasis on diabetes and metabolic syndrome. Also reviewed are aspects related to potential toxicity of which has not yet been systematically evaluated in human subjects.
L.（豆科）是一种原产于北美的灌木，主要因其观赏特性、蜜源植物价值和防止土壤侵蚀的特性而被种植。它被列为欧洲最有害的入侵物种之一。然而，越来越多的科学文献也指出其化学成分的治疗潜力。由于L.是一种具有侵略性的入侵物种，它可以提供丰富且廉价的植物化学成分资源，可用于治疗目的。此外，将其生物质用于药用可能有助于减轻该物种对自然栖息地的破坏影响。本综述的目的是提供全面的总结，并系统整理关于其植物化学成分以及在疾病治疗和预防方面潜力的最新知识，特别强调糖尿病和代谢综合征。还综述了L.潜在毒性的相关方面，而这在人体中尚未得到系统评估。
