Becker S A, Bass D, Nissim F
J Clin Gastroenterol. 1985 Aug;7(4):296-300. doi: 10.1097/00004836-198508000-00005.
We present a patient with clinically asymptomatic amyloidosis associated with Crohn's ileitis. A distinction should be made between immunocytic dyscrasia associated with amyloidosis (formerly primary or myeloma-associated amyloidosis) and acquired systemic amyloidosis (formerly secondary amyloidosis). We compare the natural course of amyloidosis complicating Crohn's disease with these complicating familial Mediterranean fever (FMF), and discuss the role of resection and the rationale behind colchicine therapy. Our patient is the first reported case in which colchicine therapy alone has been successful in the prophylactic treatment of amyloidosis complicating Crohn's ileitis.
我们报告了一名患有与克罗恩回肠炎相关的临床无症状淀粉样变性病的患者。应区分与淀粉样变性病相关的免疫细胞发育异常（以前称为原发性或骨髓瘤相关性淀粉样变性病）和获得性全身性淀粉样变性病（以前称为继发性淀粉样变性病）。我们将克罗恩病并发淀粉样变性病的自然病程与并发家族性地中海热（FMF）的情况进行了比较，并讨论了切除术的作用以及秋水仙碱治疗的理论依据。我们的患者是首例报告的仅用秋水仙碱治疗成功预防克罗恩回肠炎并发淀粉样变性病的病例。
