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1979 - 1983年苏格兰的恶性黑色素瘤

Malignant melanoma in Scotland 1979-1983.

作者信息

MacKie R M, Smyth J F, Soutar D S, Calman K C, Watson A C, Hunter J A, McLaren K M, MacGillivray J B, McPhie J L, Rankin R

出版信息

Lancet. 1985 Oct 19;2(8460):859-63. doi: 10.1016/s0140-6736(85)90126-6.

Abstract

1318 cases of primary malignant melanoma of the skin first presenting in Scotland in the years 1979-83 and registered with the Scottish Melanoma Group are described. The annual age-adjusted incidence rate is 4.75 per 100 000 for females and 2.77 per 100 000 for males. Incidence rose by an annual average of 2.5% over the five-year period. The female: male ratio was 2:1, and 48.5% of all cases were of the superficial spreading histogenetic variety. Five-year survival rates for the patients registered in 1979 confirm the prognostic value of the tumour-thickness (Breslow) measurement. They were 93% for patients with tumours less than 1.5 mm thick (39% of patients), 67% for those with tumours 1.5-3.49 mm thick (30%), and 37% for those with tumours thicker than 3.5 mm (31%). This study shows that methods for early recognition of thin tumours should be encouraged.

摘要

本文描述了1979年至1983年间首次出现在苏格兰并向苏格兰黑色素瘤研究小组登记的1318例原发性皮肤恶性黑色素瘤病例。女性的年龄调整后年发病率为每10万人4.75例,男性为每10万人2.77例。在这五年期间,发病率平均每年上升2.5%。女性与男性的比例为2:1,所有病例中48.5%为浅表扩散组织学类型。1979年登记患者的五年生存率证实了肿瘤厚度( Breslow)测量的预后价值。肿瘤厚度小于1.5mm的患者五年生存率为93%(占患者的39%),肿瘤厚度在1.5 - 3.49mm之间的患者为67%(占30%),肿瘤厚度大于3.5mm的患者为37%(占31%)。本研究表明应鼓励早期识别薄肿瘤的方法。

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