密闭式培养箱的热管理：用于评估湿度对培养箱最佳空气温度影响的新软件。

Thermal management in closed incubators: New software for assessing the impact of humidity on the optimal incubator air temperature.

作者信息

Delanaud Stéphane, Decima Pauline, Pelletier Amandine, Libert Jean-Pierre, Durand Estelle, Stephan-Blanchard Erwan, Bach Véronique, Tourneux Pierre

机构信息

PériTox UM-I 01, UFR de Médecine, Université de Picardie Jules Verne, Amiens, France.

PériTox UM-I 01, UFR de Médecine, Université de Picardie Jules Verne, Amiens, France; Réanimation et Soins Continus Pédiatriques, Pôle Femme-Couple-Enfant, CHU Amiens, Picardie, France.

出版信息

Med Eng Phys. 2017 Aug;46:89-95. doi: 10.1016/j.medengphy.2017.06.002. Epub 2017 Jun 21.

DOI:10.1016/j.medengphy.2017.06.002

PMID:28645849

Abstract

BACKGROUND

Low-birth-weight (LBW) neonates are nursed in closed incubators to prevent transcutaneous water loss. The RH's impact on the optimal incubator air temperature setting has not been studied.

METHODS

On the basis of a clinical cohort study, we modelled all the ambient parameters influencing body heat losses and gains. The algorithm quantifies the change in RH on the air temperature, to maintain optimal thermal conditions in the incubator.

RESULTS

Twenty-three neonates (gestational age (GA): 30.0 [28.9-31.6] weeks) were included. A 20% increase and a 20% decrease in the RH induced a change in air temperature of between -1.51 and +1.85°C for a simulated 650g neonate (GA: 26 weeks), between -1.66 and +1.87°C for a 1000g neonate (GA: 31 weeks), and between -1.77 and +1.97°C for a 2000g neonate (GA: 33 weeks) (p<0.001). According to regression analyses, the optimal incubator air temperature=a+b relative humidity +c age +d weight (p<0.001).

CONCLUSIONS

We have developed new mathematical equations for calculating the optimal temperature for the incubator air as a function of the latter's relative humidity. The software constitutes a decision support tool for improving patient care in routine clinical practice.

摘要

背景

低体重（LBW）新生儿在密闭培养箱中护理以防止经皮水分流失。相对湿度（RH）对培养箱最佳空气温度设置的影响尚未得到研究。

方法

基于一项临床队列研究，我们对所有影响身体热量得失的环境参数进行了建模。该算法量化了相对湿度对空气温度的变化，以维持培养箱中的最佳热条件。

结果

纳入了23名新生儿（胎龄（GA）：30.0 [28.9 - 31.6]周）。对于模拟的650克新生儿（GA：26周），相对湿度增加20%和降低20%导致空气温度变化在 -1.51至 +1.85°C之间；对于1000克新生儿（GA：31周），在 -1.66至 +1.87°C之间；对于2000克新生儿（GA：33周），在 -1.77至 +1.97°C之间（p<0.001）。根据回归分析，培养箱最佳空气温度 = a + b相对湿度 + c年龄 + d体重（p<0.001）。