口腔卫生与牙周炎的关联：系统评价和荟萃分析。
The association between oral hygiene and periodontitis: a systematic review and meta-analysis.
机构信息
Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Department of Periodontology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
出版信息
Int Dent J. 2017 Dec;67(6):332-343. doi: 10.1111/idj.12317. Epub 2017 Jun 23.
OBJECTIVE
Dental plaque accumulation and inadequate personal oral hygiene (OH) are known major risk factors of periodontitis. Nevertheless, the magnitude of their effects has not yet been the subject of a meta-analysis.
MATERIAL AND METHODS
The Medline and Scopus databases were searched up to May 2016. Observational studies were eligible if they assessed associations between OH and periodontitis in adult subjects. A multivariate random-effects meta-analysis was used to pool the effects of fair/poor OH versus good OH on periodontitis across studies. The associations between oral care habits and periodontitis were also assessed.
RESULTS
A total of 50 studies were eligible; 15 were used for pooling the effect of fair OH versus good OH and poor OH versus good OH on periodontitis, with pooled odds ratios (ORs) of 2.04 [95% confidence interval (CI): 1.65-2.53] and 5.01 (95% CI: 3.40-7.39), respectively. Eleven studies examined oral care habits measured according to toothbrushing regularity and dental visit frequency; pooled ORs of 0.66 (95% CI: 0.47-0.94) and 0.68 (95% CI: 0.47-0.98) were obtained, respectively.
CONCLUSIONS
Fair to poor OH increases the risk of periodontitis by two- to five-fold. This risk can be reduced by regular toothbrushing and dental visits.
目的
牙菌斑的积累和个人口腔卫生（OH）不足是已知的牙周炎主要危险因素。然而，它们的影响程度尚未进行荟萃分析。
材料和方法
检索 Medline 和 Scopus 数据库至 2016 年 5 月。如果观察性研究评估了 OH 与成年患者牙周炎之间的关联，则符合入选标准。使用多变量随机效应荟萃分析来汇总研究间 OH 与牙周炎之间的关联。还评估了口腔护理习惯与牙周炎之间的关系。
结果
共纳入 50 项研究，其中 15 项研究用于汇总 OH 不良与 OH 良好和 OH 差与 OH 良好对牙周炎的影响，汇总比值比（OR）分别为 2.04（95%置信区间（CI）：1.65-2.53）和 5.01（95% CI：3.40-7.39）。有 11 项研究根据刷牙频率和牙科就诊频率来检查口腔护理习惯；分别得出汇总 OR 为 0.66（95% CI：0.47-0.94）和 0.68（95% CI：0.47-0.98）。
结论
OH 不良到差会使牙周炎的风险增加两到五倍。定期刷牙和看牙医可以降低这种风险。
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