Infectious Diseases Unit, The Royal Children's Hospital Melbourne, Parkville, Australia.
Infectious Diseases Unit, The Royal Children's Hospital Melbourne, Parkville, Australia; Department of Paediatrics, The University of Melbourne, Parkville, Australia; Infectious Diseases & Microbiology and Group A Streptococcal Research Groups, Murdoch Children's Research Institute, Parkville, Australia; Centre for International Child Health, University of Melbourne, Melbourne, Australia.
J Infect. 2017 Jun;74 Suppl 1:S147-S152. doi: 10.1016/S0163-4453(17)30206-2.
Staphylococcal and streptococcal toxic shock syndrome (TSS) are associated with significant morbidity and mortality. There has been considerable progress in understanding the pathophysiology and delineating optimal management and treatment. This article reviews the management of TSS, outlining the 'Seven Rs of Managing and Treating TSS': Recognition, Resuscitation, Removal of source of infection, Rational choice of antibiotics, Role of adjunctive treatment (clindamycin and intravenous immunoglobulin), Review of progress and Reduce risk of secondary cases in close contacts.
葡萄球菌和链球菌中毒性休克综合征（TSS）与较高的发病率和死亡率相关。人们对其病理生理学有了更深入的理解，并对其最佳管理和治疗进行了明确。本文综述了 TSS 的管理，概述了“管理和治疗 TSS 的七个要点”：识别、复苏、去除感染源、合理选择抗生素、辅助治疗（克林霉素和静脉注射免疫球蛋白）的作用、评估进展和减少密切接触者中二次病例的风险。
