Liu F F, Zhao S L, Chen Q, Chang Z R, Zhang J, Zheng Y M, Luo L, Ran L, Liao Q H
Division of Infectious Disease, Key Laboratory of Surveillance and Early Warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Infectious Disease Control and Prevention Department, Hunan Provincial Center for Disease Control and Prevention, Changsha 410005, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Jun 10;38(6):754-758. doi: 10.3760/cma.j.issn.0254-6450.2017.06.013.
Through analyzing the surveillance data on typhoid fever and paratyphoid fever in 2015 to understand the related epidemiological features and most possible clustering areas of high incidence. Individual data was collected from the passive surveillance program and analyzed by descriptive statistic method. Characteristics on seasonal, regional and distribution of the diseases were described. Spatial-temporal clustering characteristics were estimated, under the retrospective space-time method. A total of 8 850 typhoid fever cases were reported from the surveillance system, with incidence rate as 0.65/100 000. The number of paratyphoid fever cases was 2 794, with incidence rate as 0.21/100 000. Both cases of typhoid fever and paratyphoid fever occurred all year round, with high epidemic season from May to October. Most cases involved farmers (39.68), children (15.89) and students (12.01). Children under 5 years showed the highest incidence rate. Retrospective space-time analysis for provinces with high incidence rates would include Yunnan, Guangxi, Guizhou, Hunan and Guangdong, indicating the first and second class clusters were mainly distributed near the bordering adjacent districts and counties among the provinces. In 2015, the prevalence rates of typhoid fever and paratyphoid fever were low, however with regional high prevalence areas. Cross regional transmission existed among provinces with high incidence rates which might be responsible for the clusters to appear in these areas.
通过分析2015年伤寒和副伤寒监测数据,了解相关流行病学特征及高发聚集区域。从被动监测项目收集个体数据,采用描述性统计方法进行分析,描述疾病的季节性、地区性及分布特征,采用回顾性时空分析方法估计时空聚集特征。监测系统共报告伤寒病例8850例,发病率为0.65/10万;副伤寒病例2794例,发病率为0.21/10万。伤寒和副伤寒病例全年均有发生,5至10月为高发季节。病例主要涉及农民(39.68)、儿童(15.89)和学生(12.01)。5岁以下儿童发病率最高。对高发省份进行回顾性时空分析,涉及云南、广西、贵州、湖南和广东,表明一级和二级聚集区主要分布在这些省份毗邻的边境区县附近。2015年,伤寒和副伤寒患病率较低,但存在区域高发地区。高发省份之间存在跨区域传播,这可能是这些地区出现聚集性病例的原因。