Christrup Lona, Sædder Eva Aggerholm
Ugeskr Laeger. 2017 Jun 26;179(26).
The total consumption of weak opioids (mainly of tramadol) in Denmark was doubled during the period 2001-2013. On the contrary, the total consumption of strong opioids remained almost constant in the same period. The increase in tramadol consumption is not rational, as it has no special benefits with regards to efficacy, side effects and abuse potential. The terms strong- and weak opioids are inappropriate, because it often erroneously is interpreted as if the weak opioids are safer, but it is really just a matter of potency: strong opioids are simply more potent.
2001年至2013年期间，丹麦弱阿片类药物（主要是曲马多）的总消费量翻了一番。相反，同期强阿片类药物的总消费量几乎保持不变。曲马多消费量的增加并不合理，因为在疗效、副作用和滥用潜力方面它并无特殊优势。强阿片类药物和弱阿片类药物这两个术语并不恰当，因为人们常常错误地认为弱阿片类药物更安全，但实际上这仅仅是效力的问题：强阿片类药物的效力更强而已。
