Cheng Yu-Ting, Chen Shao-Wei, Chang Chih-Hsiang, Chu Pao-Hsien, Chen Dong-Yi, Wu Victor Chien-Chia, Liu Kuo-Sheng, Nan Yu-Yun, Tsai Feng-Chun, Lin Pyng-Jing
Department of Cardiothoracic and Vascular Surgery, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Department of Cardiothoracic and Vascular Surgery, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Biomed J. 2017 Jun;40(3):178-184. doi: 10.1016/j.bj.2016.12.005. Epub 2017 May 31.
The percentage of patients referred for coronary artery bypass grafting (CABG) who have previously undergone percutaneous coronary interventions (PCIs) is increasing. The purpose of this study was to review the outcomes of patients who had received coronary stenting before CABG, and to examine the validity of a mortality risk stratification system in this patient group.
From 2010 to 2012, 439 patients who underwent isolated CABG at our medical center were reviewed. The patients were divided into two study groups: those who had previously received coronary artery stenting (97 patients, 24.7%), and those who had not (342 patients, 75.3%). The patients who received balloon angioplasty were excluded.
There were no significant differences in baseline characteristics. The prior stenting group had a lower risk of mortality, although the difference was not significant. The prior stenting group had fewer graft anastomoses (p = 0.005), and hence a significantly shorter cardiopulmonary bypass time (p = 0.045) and shorter aortic cross-clamping time. Surgical mortality was similar between the two groups. The durations of intensive care unit stay and hospitalization were also similar. The discriminatory power of the logistic European System for Cardiac Operative Risk Evaluation (EuroSCORE) was lower in both group.
Prior coronary stenting does not affect short-term mortality in patients subsequently undergoing CABG surgery. The EuroSCORE does not predict perioperative mortality well for the patients who undergo coronary stenting before CABG.
接受冠状动脉旁路移植术(CABG)的患者中,先前接受过经皮冠状动脉介入治疗(PCI)的患者比例正在增加。本研究的目的是回顾冠状动脉旁路移植术前接受冠状动脉支架置入术患者的预后,并检验该患者群体中死亡风险分层系统的有效性。
回顾2010年至2012年在我们医疗中心接受单纯冠状动脉旁路移植术的439例患者。患者分为两个研究组:先前接受过冠状动脉支架置入术的患者(97例,24.7%)和未接受过的患者(342例,75.3%)。接受球囊血管成形术的患者被排除。
两组患者的基线特征无显著差异。尽管差异不显著,但先前接受支架置入术的组死亡率较低。先前接受支架置入术的组移植吻合口较少(p = 0.005),因此体外循环时间显著缩短(p = 0.045),主动脉阻断时间也较短。两组的手术死亡率相似。重症监护病房住院时间和住院总时长也相似。两组中逻辑欧洲心脏手术风险评估系统(EuroSCORE)的鉴别能力均较低。
先前的冠状动脉支架置入术不影响随后接受冠状动脉旁路移植术患者的短期死亡率。对于冠状动脉旁路移植术前接受冠状动脉支架置入术的患者,EuroSCORE不能很好地预测围手术期死亡率。