• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Cannabinoid Reduces Inflammatory Cytokines, Tumor Necrosis Factor-α, and Type I Interferons in Dermatomyositis In Vitro.大麻素在体外可降低皮肌炎中的炎性细胞因子、肿瘤坏死因子-α和I型干扰素水平。
J Invest Dermatol. 2017 Nov;137(11):2445-2447. doi: 10.1016/j.jid.2017.05.035. Epub 2017 Jun 23.
2
Cytokines in juvenile dermatomyositis pathophysiology: potential and challenge.细胞因子在幼年皮肌炎病理生理学中的作用：潜力与挑战
Curr Opin Rheumatol. 2003 Nov;15(6):691-7. doi: 10.1097/00002281-200311000-00003.
3
Suppression of human monocyte interleukin-1beta production by ajulemic acid, a nonpsychoactive cannabinoid.
Biochem Pharmacol. 2003 Feb 15;65(4):649-55. doi: 10.1016/s0006-2952(02)01604-0.
4
The cannabinoid dexanabinol is an inhibitor of the nuclear factor-kappa B (NF-kappa B).大麻素右大麻酚是核因子-κB（NF-κB）的抑制剂。
Neuropharmacology. 2004 Sep;47(4):580-92. doi: 10.1016/j.neuropharm.2004.05.009.
5
The role of type I interferons and other cytokines in dermatomyositis.I型干扰素及其他细胞因子在皮肌炎中的作用。
Cytokine. 2015 Jun;73(2):319-25. doi: 10.1016/j.cyto.2014.11.026. Epub 2014 Dec 23.
6
Levels of cytokine inhibitors: a possible marker of disease activity in childhood dermatomyositis and polymyositis.细胞因子抑制剂水平：儿童皮肌炎和多发性肌炎疾病活动的一个可能标志物。
Clin Exp Rheumatol. 1997 Mar-Apr;15(2):211-4.
7
Lack of response suppression follows repeated ventral tegmental cannabinoid administration: an in vitro electrophysiological study.重复给予腹侧被盖区大麻素后缺乏反应抑制：一项体外电生理研究。
Neuroscience. 2000;99(4):661-7. doi: 10.1016/s0306-4522(00)00241-4.
8
Interferons as components of the complex web of reactions sustaining inflammation in idiopathic inflammatory myopathies.干扰素作为特发性炎性肌病中维持炎症反应复杂网络的组成部分。
Cytokine. 2015 Jul;74(1):81-7. doi: 10.1016/j.cyto.2014.10.012. Epub 2014 Dec 4.
9
Correlation of cutaneous disease activity with type 1 interferon gene signature and interferon β in dermatomyositis.皮肌炎中皮肤疾病活动与 1 型干扰素基因特征和干扰素-β的相关性。
Br J Dermatol. 2017 May;176(5):1224-1230. doi: 10.1111/bjd.15006. Epub 2017 Mar 14.
10
Cannabinoids and brain injury: therapeutic implications.大麻素与脑损伤：治疗意义
Trends Mol Med. 2002 Feb;8(2):58-61. doi: 10.1016/s1471-4914(02)02276-1.

引用本文的文献

1
CAR-T cell therapy in rheumatic diseases: a review article.风湿性疾病中的嵌合抗原受体T细胞疗法：一篇综述文章。
Clin Rheumatol. 2025 Apr 26. doi: 10.1007/s10067-025-07451-7.
2
Geraniol modulates inflammatory and antioxidant pathways to mitigate intestinal ischemia-reperfusion injury in male rats.香叶醇调节炎症和抗氧化途径以减轻雄性大鼠的肠道缺血再灌注损伤。
Naunyn Schmiedebergs Arch Pharmacol. 2025 Jan 22. doi: 10.1007/s00210-025-03802-y.
3
Long-Term Safety and Efficacy of Lenabasum, a Cannabinoid Receptor Type 2 Agonist, in Patients with Dermatomyositis with Refractory Skin Disease: Follow-Up Data from a 3-Year Open-Label Extension Study.大麻素2型受体激动剂来那巴松治疗皮肤难治性皮肌炎患者的长期安全性和有效性：一项为期3年的开放标签扩展研究的随访数据
JID Innov. 2024 Sep 5;5(1):100311. doi: 10.1016/j.xjidi.2024.100311. eCollection 2025 Jan.
4
Updates in Dermatomyositis: Newer Treatment Options and Outcome Measures From Dermatologic Perspectives.皮肌炎的最新进展：从皮肤科角度看新的治疗选择和疗效评估指标
Ann Dermatol. 2024 Oct;36(5):257-265. doi: 10.5021/ad.24.022.
5
Green Smoke, Red Flag: Cannabis and the Risk of Orbitopathy and Dermopathy in Thyrotoxicosis.绿烟，红旗：大麻与甲状腺毒症性眼眶病和皮肤病的风险
Cureus. 2023 May 16;15(5):e39092. doi: 10.7759/cureus.39092. eCollection 2023 May.
6
Cannabidiol's neuroprotective properties and potential treatment of traumatic brain injuries.大麻二酚的神经保护特性及对创伤性脑损伤的潜在治疗作用。
Front Neurol. 2023 Feb 2;14:1087011. doi: 10.3389/fneur.2023.1087011. eCollection 2023.
7
Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases.大麻素化合物作为治疗非癌症皮肤疾病的一种药物治疗选择。
Cells. 2022 Dec 16;11(24):4102. doi: 10.3390/cells11244102.
8
Safety and Efficacy of Lenabasum, a Cannabinoid Receptor Type 2 Agonist, in Patients with Dermatomyositis with Refractory Skin Disease: A Randomized Clinical Trial.大麻素受体 2 激动剂利纳巴斯治疗伴有难治性皮肤疾病的皮肌炎患者的安全性和疗效：一项随机临床试验。
J Invest Dermatol. 2022 Oct;142(10):2651-2659.e1. doi: 10.1016/j.jid.2022.03.029. Epub 2022 Apr 29.
9
COL8A1 Promotes NSCLC Progression Through IFIT1/IFIT3-Mediated EGFR Activation.COL8A1通过IFIT1/IFIT3介导的EGFR激活促进非小细胞肺癌进展。
Front Oncol. 2022 Feb 24;12:707525. doi: 10.3389/fonc.2022.707525. eCollection 2022.
10
Cannabinoids for the Treatment of Dermatologic Conditions.用于治疗皮肤病的大麻素类药物。
JID Innov. 2022 Jan 13;2(2):100095. doi: 10.1016/j.xjidi.2022.100095. eCollection 2022 Mar.

本文引用的文献

1
Ultrapure ajulemic acid has improved CB2 selectivity with reduced CB1 activity.超纯阿九酸提高了CB2选择性，同时降低了CB1活性。
Bioorg Med Chem. 2014 Jul 1;22(13):3245-51. doi: 10.1016/j.bmc.2014.04.062. Epub 2014 May 9.
2
Gottron's papules exhibit dermal accumulation of CD44 variant 7 (CD44v7) and its binding partner osteopontin: a unique molecular signature.Gottron 丘疹表现为 CD44 变体 7（CD44v7）及其结合伴侣骨桥蛋白在真皮中的蓄积：一种独特的分子特征。
J Invest Dermatol. 2012 Jul;132(7):1825-32. doi: 10.1038/jid.2012.54. Epub 2012 Mar 29.
3
Tumor necrosis factor α release in peripheral blood mononuclear cells of cutaneous lupus and dermatomyositis patients.皮肤狼疮和皮肌炎患者外周血单个核细胞中肿瘤坏死因子α的释放。
Arthritis Res Ther. 2012 Jan 4;14(1):R1. doi: 10.1186/ar3549.
4
Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines.疟原虫药物和咪唑喹啉对内体 TLR 抑制的作用机制。
J Immunol. 2011 Apr 15;186(8):4794-804. doi: 10.4049/jimmunol.1000702. Epub 2011 Mar 11.
5
Ajulemic acid, a synthetic cannabinoid, increases formation of the endogenous proresolving and anti-inflammatory eicosanoid, lipoxin A4.阿久米酸，一种合成大麻素，可增加内源性促分解和抗炎类二十烷酸脂氧素A4的生成。
FASEB J. 2009 May;23(5):1503-9. doi: 10.1096/fj.08-118323. Epub 2009 Jan 5.
6
Ajulemic acid, a synthetic cannabinoid acid, induces an antiinflammatory profile of eicosanoids in human synovial cells.阿久米酸，一种合成大麻素酸，可诱导人滑膜细胞中类花生酸产生抗炎特性。
Life Sci. 2008 Nov 7;83(19-20):666-70. doi: 10.1016/j.lfs.2008.09.004. Epub 2008 Sep 21.
7
Suppression of human macrophage interleukin-6 by a nonpsychoactive cannabinoid acid.
Rheumatol Int. 2008 May;28(7):631-5. doi: 10.1007/s00296-007-0489-0. Epub 2007 Nov 27.
8
Ajulemic acid, a nonpsychoactive cannabinoid acid, induces apoptosis in human T lymphocytes.阿久米酸，一种非精神活性大麻素酸，可诱导人T淋巴细胞凋亡。
Clin Immunol. 2003 Aug;108(2):95-102. doi: 10.1016/s1521-6616(03)00064-0.
9
Suppression of human monocyte interleukin-1beta production by ajulemic acid, a nonpsychoactive cannabinoid.
Biochem Pharmacol. 2003 Feb 15;65(4):649-55. doi: 10.1016/s0006-2952(02)01604-0.
10
TNFalpha-308A allele in juvenile dermatomyositis: association with increased production of tumor necrosis factor alpha, disease duration, and pathologic calcifications.青少年皮肌炎中的肿瘤坏死因子α-308A等位基因：与肿瘤坏死因子α产生增加、疾病持续时间及病理性钙化的关联
Arthritis Rheum. 2000 Oct;43(10):2368-77. doi: 10.1002/1529-0131(200010)43:10<2368::AID-ANR26>3.0.CO;2-8.

Cannabinoid Reduces Inflammatory Cytokines, Tumor Necrosis Factor-α, and Type I Interferons in Dermatomyositis In Vitro.

作者信息

Robinson Elizabeth S, Alves Paul, Bashir Muhammad M, Zeidi Majid, Feng Rui, Werth Victoria P

机构信息

Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

出版信息

J Invest Dermatol. 2017 Nov;137(11):2445-2447. doi: 10.1016/j.jid.2017.05.035. Epub 2017 Jun 23.

DOI:10.1016/j.jid.2017.05.035
PMID:28652111
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5651184/
Abstract
摘要