Yu Amy, Fahimian Benjamin, Million Lynn, Hsu Annie
Department of Radiation Oncology, Stanford University School of Medicine.
Cureus. 2017 May 23;9(5):e1270. doi: 10.7759/cureus.1270.
Purpose Radiotherapy treatment planning of extended volume typically necessitates the utilization of multiple field isocenters and abutting dosimetrically matched fields in order to enable coverage beyond the field size limits. A common example includes total lymphoid irradiation (TLI) treatments, which are conventionally planned using dosimetric matching of the mantle, para-aortic/spleen, and pelvic fields. Due to the large irradiated volume and system limitations, such as field size and couch extension, a combination of couch shifts and sliding of patients are necessary to be correctly executed for accurate delivery of the plan. However, shifting of patients presents a substantial safety issue and has been shown to be prone to errors ranging from minor deviations to geometrical misses warranting a medical event. To address this complex setup and mitigate the safety issues relating to delivery, a practical technique for couch indexing of TLI treatments has been developed and evaluated through a retrospective analysis of couch position. Methods The indexing technique is based on the modification of the commonly available slide board to enable indexing of the patient position. Modifications include notching to enable coupling with indexing bars, and the addition of a headrest used to fixate the head of the patient relative to the slide board. For the clinical setup, a Varian Exact Couch (Varian Medical Systems, Inc, Palo Alto, CA) was utilized. Two groups of patients were treated: 20 patients with table indexing and 10 patients without. The standard deviations (SDs) of the couch positions in longitudinal, lateral, and vertical directions through the entire treatment cycle for each patient were calculated and differences in both groups were analyzed with Student's t-test. Results The longitudinal direction showed the largest improvement. In the non-indexed group, the positioning SD ranged from 2.0 to 7.9 cm. With the indexing device, the positioning SD was reduced to a range of 0.4 to 1.3 cm (p < 0.05 with 95% confidence level). The lateral positioning was slightly improved (p < 0.05 with 95% confidence level), while no improvement was observed in the vertical direction. Conclusions The conventional matched field TLI treatment is error-prone to geometrical setup error. The feasibility of full indexing TLI treatments was validated and shown to result in a significant reduction of positioning and shifting errors.
目的 扩大照射体积的放射治疗计划通常需要使用多个射野等中心和剂量学匹配的相邻射野,以便能够覆盖超出射野尺寸限制的范围。一个常见的例子包括全淋巴照射(TLI)治疗,传统上是通过对斗篷野、腹主动脉旁/脾脏野和盆腔野进行剂量学匹配来制定计划的。由于照射体积大以及系统限制,如射野尺寸和治疗床延伸,为了准确实施计划,需要正确执行治疗床移动和患者滑动的组合操作。然而,患者移动带来了重大安全问题,并且已被证明容易出现从轻微偏差到几何误差等各种错误,这可能引发医疗事件。为了解决这一复杂的摆位问题并减轻与治疗实施相关的安全问题,通过对治疗床位置的回顾性分析,开发并评估了一种用于TLI治疗的治疗床索引实用技术。方法 该索引技术基于对常用滑板的改进,以实现患者位置的索引。改进包括开槽以便与索引杆耦合,以及增加一个头枕用于将患者头部相对于滑板固定。对于临床摆位,使用了瓦里安精确治疗床(瓦里安医疗系统公司,加利福尼亚州帕洛阿尔托)。治疗了两组患者:20例采用治疗床索引的患者和10例未采用的患者。计算了每位患者在整个治疗周期中治疗床位置在纵向、横向和垂直方向上的标准差(SD),并使用学生t检验分析两组之间的差异。结果 纵向方向显示出最大的改善。在未索引组中,定位标准差范围为2.0至7.9厘米。使用索引装置后,定位标准差降至0.4至1.3厘米的范围(95%置信水平下p < 0.05)。横向定位略有改善(95%置信水平下p < 0.05),而在垂直方向未观察到改善。结论 传统的匹配野TLI治疗容易出现几何摆位误差。全索引TLI治疗的可行性得到验证,并显示可显著减少定位和移动误差。